Our research team is active in research in the areas of
chronic kidney disease epidemiology, diabetes nephropathy prognostic biomarkers
and glomerulonephritis clinical outcomes, with funding from national and
institutional competitive grants. We also have active collaborations with the
Singapore Clinical Research Institute (SCRI), Singapore Eye Research Institute
(SERI), Duke-National University of Singapore (Duke-NUS) Graduate School in
investigator-initiated studies, in addition to sponsored clinical trials. Research
projects are supported by the Clinical Trial Research Center (CTRC),
Investigative Medicine Unit (IMU), Health Service Research Unit (HSRU),
Medicine Academic Clinical Program (ACP) and the Renal Research Laboratory.
Our Critical Care Nephrology research team focuses on risk
factors associated with acute kidney injury.
Our physicians conduct research in dialysis technology to
improve patient-centric outcomes. Our projects include developing “Automated
Wearable Artificial Kidney Peritoneal Dialysis (AWAK PD) in the Treatment of
End-Stage Renal Disease (ESRD) Patients”, “Novel Hole Access Device to Preserve
Vascular Access and Reduce Cost for Hemodialysis”. The research projects are sponsored by
Ministry of Health, National Kidney Foundation, A*STAR and other resources.
In addition, we collaborate closely with the Health Service
Research team in Duke-National University of Singapore (Duke-NUS) Graduate
School in evaluating cost-effective dialysis practices.
Our research on improvement of vascular access, prolonging
access survival and reduce technique failure through experimental and devices
trials have earned recognition from international and regional conferences. Our
collaborators include researchers from A*STAR and other hospitals.
As the largest pioneer transplant center in the country , the
transplant program has ongoing research on transplant health system research, patient
immunophenotypes and immunosuppressant pharmacogenomics, diagnostic novel biomarkers, and the use of
viral-specific cytolytic T-cell therapies.
These projects, with the vision to improve patient care and experience, are
supported by the National Kidney Foundation and Lee Foundation. The transplant
program is also involved in multicenter clinical trials on optimizing
immunosuppression, the most recent being the TRANSFORM trial which is the
largest multicenter clinical trial in kidney transplantation. It is also active
in quality improvement projects, several which have received awards for
improving work processes and patient care.