HOMOVANILLIC ACID (HVA), URINE

24 hr urine specimen in 15 mL 50% HCl or random urine.

Minimum aliquot volume : 30 mL urine

Total 24 hr urine volume must be clearly indicated

​High Performance Liquid Chromatography

​0 – 1 yr : < 20.2 µmol/mmol creatinine

2 – 4 yrs : < 13.6 µmol/mmol creatinine

5 – 9 yrs : < 9.4 µmol/mmol creatinine

10 – 19 yrs : < 7.9 µmol/mmol creatinine

≥ 20 yrs : < 45.6 µmol/day

​Mean = 7 days, Range: 3 - 11 days

​Monday – Friday

Patient Preparation:

(1) Patient Should abstain from the following at least 3 days prior to and during urine specimen collection:

(a) where medically possible, drugs containing phenotiazines which may potentially interfere with the testing.

(2) If the patient cannot be completely removed from a drug regime, test result should be interpreted with appropriate clinical judgement based on expected physiology response to these drugs.