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During the war, there was a severe shortage of anti-Diphtheria serum. With ingenuity, Prof Monteiro injected filtered toxin from the bacterial cultures into the jugular veins of some goats and bled them 3 weeks later to obtain the serum which he froze and used successfully to combat the epidemic that was spreading throughout Syonan-to (as Singapore was known during the Japanese Occupation).
Soon after WWII, common infectious diseases like Diphtheria took a heavy toll on lives of the children of Singapore. Prof Monteiro had fully expected that the scheme of inoculating pre-school and school children with anti-Diphtheria toxoid by the Singapore Municipality Health Department would work. However, the scheme was only a voluntary one, it did not achieve its desired effects.
Prof Monteiro insisted on making anti-Diphtheria inoculation compulsory with the force of the law in a joint meeting with the Public Health officials of both Singapore and the Federation of Malaya.
Prof Monteiro succeeded in making anti-Diphtheria inoculation a legal requirement in Singapore.
Another major pioneering medical achievement was his decision to use the untested oral Sabin vaccine on a massive scale to combat the acute anterior poliomyelitis outbreak in Singapore.
A quarter million children were immunised and the epidemic was brought to an end.
| Acronym | Term |
| CBE | Commander of the British Empire (in 1957) |
| LMS | Licentiate in Medicine and Surgery |
| MD | Doctor of Medicine (Malaya) |
| FRCP | Fellow of the Royal College of Physicians (London) & (Glasgow) |
| DCH | Diploma in Child Health (London) |
| FRSH | Fellow of the Royal Society of Health (England) |
| AM | Ambassador to Cambodia, USA and Brazil (in 1965 - 1977) |
| FRFPS | Fellowship of the Royal Faculty of Physicians & Surgeons |
| BBM | Bintang Bakti Masyarakat or Public Service Star (in 1963) |
| PJG | Pingat Jasa Gemilang or Meritorious Service Medal (in 1968) |
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