Our Researchers

​Dr Michelle Tan Guet Khim

Senior Principal Research Scientist

 michelle.tan.g.k@sgh.com.sg

Expertise:

• Cell biology and cellular imaging  
• Molecular and proten biology
  
• Immunophenotyping using flow cytometry analysis
  
• Biomarker discovery
  

 Research Focus:

• Selective targeting isoform-specific FynT tyrosine kinase for Alzheimer’s disease and tauopathies-related dementias  
  
• Biomarker discovery for Alzheimer’s disease and vascular dementia
  
• Exploring the role of peripheral immune system In modulating neuroinflammation, neurodegeneration and cognitive functions
  

​Ms Lai Oi Fah

Principal Research Scientist

 lai.oi.fah@sgh.com.sg

Expertise:

• Biomarker discovery
  
• Luminex assays
  

 Research Focus:

​Dr Fan Xiubo 

Senior Research Fellow I 

 fan.xiubo@sgh.com.sg

Expertise:

• Handling animal models, such as mouse model of graft-versus-host disease (GvHD), systemic lupus erythematosus (SLE) and systemic sclerosis (SSc)
• Running RNA sequence (both bulk and single cell levels)
• Running flow cytometric assays
• Running Luminex, PCR and Western Blot
  

 Research Focus:

• Inflammatory diseases therapy with mesenchymal stromal cells (MSCs) and hematopoietic stem cells (HSCs) transplant
• Inflammatory diseases therapy with MSC-derived molecules
  

​Dr Poon Zhi Yong 

Senior Research Fellow I 

 poon.zhi.yong@sgh.com.sg

Expertise:

• Stem cell biology (MSCs, HSPCs)
  
• Cancer biology
  
• Cell-based therapies for cancer or regenerative medicines (MSCs, T-cells, HSPCs)
  
• Drug and gene delivery
  

 Research Focus:

• MSC-HSPC interplay during the development of blood cancers
  
• Modulation of stem/T-cell properties to optimize cell-therapies and technologies that aid their manufacturing/preservation
  
• Development of gene/crispr medicines
  

​Dr Lim Che Kang

Senior Research Associate

 lim.che.kang@sgh.com.sg 

Expertise: 

• Bioinformatics analysis and statistical analysis. Including, Multi-omics analysis, high-throughput sequencing data (NGS data), GWAS etc.
• Immunology and immunogenetic experimental designed and lab skills.
• Problem solving, analytical and critical thinking. 
  

 Research Focus:

• Clinical Immunology and Immunogenetics
• Bioinformatics and multi-omics analysis (including genomic (e.g. germline and somatic mutation analysis), epigenetics, transcriptomics and epitranscriptomics.)
  
• Immunology disorders including Autoimmune disorders & Primary immunodeficiency diseases
• Cancer Immunology (including cancer neoantigen analysis)