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Dr Kenneth Chen

Dr Kenneth Chen

​MBBS (S’pore), MRCS (Edin), MCI, DFD (CAW), FRCS (Glas), FAMS (Urol)


Singapore General Hospital

Specialty: Surgery & Surgical Oncology, Urology

Sub-specialties: Uro-Oncology, Minimally Invasive Surgery

Conditions Treated by this Doctor:
Adrenal Gland Cancer, Benign Prostatic Hyperplasia (BPH), Bladder Cancer, Kidney Cancer, Penile Cancer, Prostate Cancer, Robotic and Laparoscopic Surgery, Testicular Cancer, Urological Cancers.

Clinical Appointments

  • Consultant Urology Singapore General HospitalSingapore General Hospital
  • Consultant Division of Surgery & Surgical Oncology National Cancer Centre SingaporeNational Cancer Centre Singapore


​Dr Chen obtained membership of the Royal College of Surgeons (MRCS Edinburgh) in 2010 and Fellowship of the Royal College of Surgeons (Glasgow) and more recently has completed the Masters of Clinical Investigation (MCI) course with National University of Singapore on a NMRC MOH Healthcare Research Scholarship. He has completed his 6-year residency in Urology with SingHealth and has cleared his specialist exit exams with distinction, having obtained the College of Surgeons GOLD medal for best performing advanced surgical trainee in Urology.

His academic output includes teaching medical students in his capacity as a Clinical Lecturer at Yong Loo Lin School of Medicine and Lee Kong Chian School of Medicine, as well as a Clinical Assistant Professor with Duke-NUS Medical School.

Dr Chen's research interest comprises a mix of basic science as well as translational and clinical components in the area of uro-oncology as well as novel device development and is currently under the Nurturing Clinician Scientist Scheme under SingHealth Surgery ACP grant working on developing a novel drug-eluting ureteral stent for ureteric strictures and upper tract urothelial cancers. His other area of interest is in the field of metastatic prostate cancer and he is developing the department’s dedicated metastatic prostate cancer service.


  • ​Fellow of Academy of Medicine Singapore
  • Masters of Clinical Investigation (NUS)
  • Fellow of Royal College of Surgeons (Glasgow) (Urology)
  • Member of Royal College of Surgeons (Edinburgh) 
  • Bachelor of Medicine, Bachelor of Surgery (NUS)

Professional Appointments and Committee Memberships

  • Clinical Assistant Professor with Duke-NUS Medical School
  • Clinical Lecturer with National University of Singapore Yong Loo Lin School of Medicine
  • Adjunct Teaching Faculty with Lee Kong Chian School of Medicine
  • SingHealth Physician Faculty for PGY1 Program - Urology
  • Physician Faculty for Singhealth Urology Residency Program
  • Member of Singapore General Hospital P&T committee
  • Member of Singapore Urological Association
  • Member of Singapore General Hospital Medical Board 2019


  • ​Singapore Health Quality Service Award (Gold)
  • Singapore Health Quality Service Award (Silver)
  • Nurturing Clinician Scientist Scheme (Singhealth Surgery ACP)
  • NMRC MOH Healthcare Research Scholarship (MCI program)
  • College of Surgeons Singapore GOLD Medal in Urology (Best performing advanced surgical trainee in Urology)
  • Outstanding Resident Award (Singhealth Residency Program)

Research Interests

  • ​Novel Device Development
  • Drug eluting ureteric stents
  • Prostate Cancer Diagnostics
  • Biomarkers in prostate cancer,
  • Multidisciplinary Care in Metastatic Prostate Cancer


  1. ​Tan YG, Poon RJ, Pang LJ, Villanueva A, Huang HH, Chen K, Ng TK, Tay KJ, Ho HS, Yuen JS. Comparative study of surgical orchidectomy and medical castration in treatment efficacy, adverse effects and cost based on a large prospective metastatic prostate cancer registry. Urol Oncol. 2020 Aug;38(8):682.e1-682.e9. doi: 10.1016/j.urolonc.2020.05.005. Epub 2020 May 29.PMID: 32475745
  2. Lee AY, Yang XY, Lee HJ, Law YM, Hong HH, Lau WK, Lee LS, Ho HS, Tay KJ, Cheng CW, Yuen JS, Chen K. Multiparametric MRI-Ultrasound Software Fusion Prostate Biopsy - Initial Results Using A Stereotactic Robotic Assisted Transperineal Prostate Biopsy Platform Comparing Systematic Versus Targeted Biopsy. BJU Int. 2020 May 21. doi: 10.1111/bju.15118. Online ahead of print.PMID: 32438463
  3. Yu Guang Tan, Mohamad Farhan Bin Khalid, Andre Villanueva, Hong Hong Huang, Kenneth Chen and Allen Soon Phang Sim. Are small renal masses all the same? Int J Urol. 2020 May;27(5):439-447. doi: 10.1111/iju.14219. Epub 2020 Mar 23. PMID: 32207186
  4. Tan YG, Pang L, Khalid F, Poon R, Huang HH, Chen K, Tay KJ, Lau W, Cheng C, Ho H, Yuen J. Local and systemic morbidities of de novo metastatic prostate cancer in Singapore: insight from 685 consecutive patients from a large prospective Uro-oncology registry. BMJ Open. 2020 Feb 18;10(2):e034331. doi: 10.1136/bmjopen-2019-034331.
  5. Yang X, Lee AY, Law YM, Sim ASP, Tay KJ, Lau WKO, Ho HSS, Yuen JSP, Chen K. Stereotactic robot-assisted transperineal prostate biopsy under local anaesthesia and sedation: moving robotic biopsy from operating theatre to clinic. J Robot Surg. 2020 Feb 12. doi: 10.1007/s11701-020-01052-z. [Epub ahead of print]
  6. Lee A, Lee HJ, Huang HH, Tay KJ, Lee LS, Sim SPA, Ho SSH, Yuen SPJ, Chen K. Prognostic Significance of Inflammation-associated Blood Cell Markers in Nonmetastatic Clear Cell Renal Cell Carcinoma. Clin Genitourin Cancer. 2019 Dec 4. pii: S1558-7673(19)30364-7. doi: 10.1016/j.clgc.2019.11.013.
  7. Tung JYM, Chen K, Sim ASP. Indocyanine green - guided laparoscopic renal pedicle lymphatic disconnection: A novel, targeted treatment for chyluria. Int Braz J Urol. 2019 Mar 20;45.
  8. Lee A, Lee HJ, Huang HH, Ho H, Chen K. Low-risk Non-muscle Invasive Bladder Cancer – Further Prognostic Stratification into “Very Low-risk” group based on tumour size. Int J Urol. 2019 Apr;26(4):481-486.
  9. Chen K, Xin Yan Yang, Karine Sim, Mahmood B. Mohammad, Kae Jack Tay, Allen Sim, Yuen SP J. Total Extra-peritoneal (TEP) Robotic-assisted LaparoscopicRadical Prostatectomy – Step-by-step Approach. Journal of Endourology, Part B:Videourology Vol. 33, No. 2. Published Online:27 Mar 2019
  10. Chen K, Lee A, Huang HH, Tay KJ, Sim A, Lee LS, Cheng C, Ng LG, Ho H, Yuen SP J. Evolving trends in the surgical management of renal masses over the last two decades: a contemporary picture from a large prospectively-maintained database. Int J Urol. 2019 Apr;26(4):465-474.
  11. Jin Yong, Chen K, Allen Sim, Endoscopic Management of Giant Bladder Stones:The Elegant Choice, Videourology Vol 33, No. 1. Published Online:30 Jan 2019.
  12. Lee HJ, Chen K, Molchanov R, Schwentner C, Sim ASP. Feasibility of utilizing near-infrared fluorescence imaging with indocyanine green for super-selective arterial clamping in pure laparoscopic partial nephrectomy. Int J Urol. 2018 Apr;25(4):382-383. doi: 10.1111/iju.13525.
  13. Chen K, Tan YG, Tan D, Pek G, Huang HH, Sim AS A. Predictors and outcomes of laparoscopic nephrectomy in autosomal dominant polycystic kidney disease. Investig Clin Urol. 2018 Jul;59(4):238-245.
  14. Chen K, Lim WS, Chong Tsung Wen et al. A bilayer swellable drug-eluting ureteric stent: Localized drug delivery to treat urothelial diseases. Biomaterials 2018. Biomaterials. 2018 May;165:25-38. doi: 10.1016/j.biomaterials.2018.02.035.
  15. Chen K, Tay KJ, Law YM, Aydin H, Ho H, Cheng C, Yuen JS. Outcomes of Combination MRI-targeted and Transperineal Template Biopsy in Restaging Low-risk Prostate Cancer for Active Surveillance. Asian J Urol. 2018 Jul;5(3):184-193.
  16. Chen K, Sim A, Kan AF. The effect of adjunct caudal block on postoperative analgesia in robot-assisted laparoscopic radical prostatectomy: a prospective randomized controlled, single blinded study in a tertiary centre. Asian J Urol. 2018 Apr;5(2):122-126. doi: 10.1016/j.ajur.2017.06.009.
  17. Chen K, Lee BL, Huang HH, Tan BY, Lee LS, Ng LG, Lau W, Yuen JS. Tumor size and Fuhrman grade further enhance the prognostic impact of perinephric fat invasion and renal vein extension in T3a staging of renal cell carcinoma. Int J Urol. Volume 24, Issue 1 January 2017 Pages 51–58
  18. Chen K, Huang HH, Aydin H, Tan YH, Lau WK, Cheng CW, Yuen JS. Renal cell carcinoma in patients with end-stage renal disease is associated with more favourable histological features and prognosis. Scand J Urol. 2015 Mar 17:1-5.
  19. Chen K, Eu E, Tan YG, Ho H, Sim A, Schwentner C. "Zero-ischemialaparoscopic partial nephrectomy with hydrodissection: technique and earlyexperience from a multicentre study" Videourology Vol. 32, No. 1. Published online 1 Feb 2018
  20. Tiwari Raj, Chen K, Phang Allen Sim Soon. Zero Ischemia, IndocyaninGreen-Assisted Robotic Heminephroureterectomy for a Duplicated Renal CollectingSystem. Videourology, Vol. 32, No. 2. Published online 6 Apr 2018.
  21. Lee Han Jie, Chen Kenneth, Molchanov Robert, Schwentner Christian, Soon Phang Sim, Allen. (2018). Feasibility of utilizing near-infrared fluorescence imaging with indocyanine green for super-selective arterial clamping in pure laparoscopic partial nephrectomy. Int J Urol. 2018 Apr;25(4):382-383.
  22. Fong SS, Chen K, Sim R, Chronic anastomotic sinus after low anterior resection: When can the defunctioning stoma be reversed? Colorectal Dis. 2011 Jun;13(6):644-9. doi: 10.1111/j.1463-1318.2010.02245.x. Epub 2010 Feb 20.
  23. Tan KK, Chen K, Liau KH, Ho CK, Pancreatic tuberculosis mimicking pancreatic carcinoma: series of three cases, Eur J Gastroenterol Hepatol. 2009 Nov;21(11):1317-9.
  24. Tan KK, Chen K, Chia KH, Lee CW, Nalachandran S., Surgical management of infected pseudoaneurysms in intravenous drug abusers: single institution experience and a proposed algorithm, World J Surg. 2009 Sep;33(9):1830-5.
  25. Tan KK, Chen K, Sim R., The spectrum of abdominal tuberculosis in a developed country: a single institution's experience over 7 years, J Gastrointest Surg. 2009 Jan;13(1):142-7.

Research Trials