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Dr Melinda Tan

Dr Tan Si Yun, Melinda

​​MD, MMed(Int Med), MRCP(UK)


Singapore General Hospital

Specialty: Haematology

Clinical Interest: Lymphoma, Myeloma, Laboratory Haematology

Conditions Treated by this Doctor:
Acute Lymphocytic Leukemia (ALL), Aplastic Anaemia, Chronic lymphocytic leukemia, Chronic Myeloid Leukemia, Deep Vein Thrombosis, Deep Vein Thrombosis, Essential Thrombocythemia and Myelofibrosis, Lymphoma, Multiple Myeloma, Myelodysplastic Syndrome, Myelofibrosis, Myeloma, Polycythemia Vera, Thalassemia.

Clinical Appointments

  • Consultant SingHealth Duke-NUS Blood Cancer Centre
  • Consultant Haematology Singapore General HospitalSingapore General Hospital
  • Consultant National Cancer Centre SingaporeNational Cancer Centre Singapore


​Dr Tan received her medical training at the Duke-NUS Medical School. She subsequently joined the department of Haematology as it provides her with the opportunity to treat a wide range of blood disorders, and marries the best of clinical and laboratory medicine. She has a special interest in multiple myeloma and flow cytometry. 


Professional Appointments and Committee Memberships

  • Clinical Tutor – Yong Loo Lin School of Medicine, NUS
  • Clinical Instructor – Duke-NUS Medical School


  • Singhealth Health Quality Service HERO awards 2021
  • Service Quality Award (Silver) 2019

Research Interests


  • Ong SY, de Mel S, Grigoropoulos NF, Chen Y, Tan YC, Tan MSY, et al. High-dose methotrexate is effective for prevention of isolated CNS relapse in diffuse large B cell lymphoma. Blood Cancer J [Internet]. 2021 Aug 12;11(8):143. Available from:
  • Chen Y, Nagarajan C, Tan MS, Martinelli G, Cerchione C. BCMA-targeting approaches for treatment of multiple myeloma. Panminerva Med [Internet]. 2021 Mar;63(1):28–36. Available from:
  • Jaya-Bodestyne SL, Lee LH, Tan LK, Tan KH, Østbye T, Malhotra R, et al. Risk factors for pregnancy-associated venous thromboembolism in Singapore. J Perinat Med [Internet]. 2021 Feb 23;49(2):153–8.
  • Chen Y, Gopalakrishnan SK, Ooi M, Sultana R, Lim LH, Grigoropoulos N, et al. A phase 2 study of carfilzomib, cyclophosphamide and dexamethasone as frontline treatment for transplant-eligible MM with high-risk features (SGH-MM1). Vol. 11, Blood cancer journal. 2021. p. 150.
  • Nagarajan C, Tan MS, Chen Y, Martinelli G, Cerchione C. Current and future perspectives of maintenance therapy in multiple myeloma. Panminerva Med [Internet]. 2020 Dec;62(4):225–33.
  • Jen W-Y, Yoong J, Liu X, Tan MSY, Chng WJ, Chee Y-L. Qualitative Study of Factors Affecting Patient, Caregiver and Physician Preferences for Treatment of Myeloma and Indolent Lymphoma. Patient Prefer Adherence [Internet]. 2020;14:301–8. Available from:
  • Chew M-H, Koh P-K, Tan M, Lim K-H, Carol L, Tang C-L. Mismatch repair deficiency screening via immunohistochemical staining in young Asians with colorectal cancers. World J Surg. 2013 Oct;37(10):2468–75.
  • Tan MSY, Narasimhalu K, Ong SYK. Letting the cat out of the bag: shifting practices of cancer disclosure in Singapore. Singapore Med J. 2012 May;53(5):344–8.

Research Trials