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VANILLYLMANDELIC ACID (VMA), URINE

Synonym(s):

Lab Section Category

Description

Indications

Specimen Required

​24 hr urine in 15 mL 50% HCl

Minimum aliquot volume : 30 mL urine

Total 24 hr urine volume must be clearly indicated

Storage and Transport

Method

​High Performance Liquid Chromatography

Test Results

Reference Interval / Value

​0 – 1 yr : < 10.7 µmol/mmol creatinine

2 – 4 yrs : < 6.3 µmol/mmol creatinine

5 – 9 yrs : < 4.7 µmol/mmol creatinine

10 – 19 yrs : < 4.7 µmol/mmol creatinine  

≥ 20 yrs : < 34.3 µmol/day                    

Turnaround Time

​Mean = 7 days, Range: 3 – 11 days

Day(s) Test Set up

​Monday – Friday

Remarks

​Instructions before sampling

Patient Preparation:
1. Patient should abstain from the following at least 3 days prior to and during urine specimen collection:
a) intake of food like bananas, vanilla, chocolate, cofee and tea
b) where medically possible, drugs such as  drugs containing phenotiazines, gentisic or homogentisic acid which may potentially interfere with the testing.

2. If the patient cannot be completely removed from a drug regime, test result should be interpreted with appropriate clinical judgement based on expected physiology response to these drugs.

Change History Notes

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