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T AND B CELL CLONALITY

Synonym(s):

Description

Indications

​The T & B Cell Clonality is intended for PCR-based detection of clonal IGH chain, IGK light chain, TCRB chain and TCRG chain gene rearrangements in patients with suspect lymphoproliferations.

Specimen Required

​Send formalin fixed paraffin embedded (FFPE) tissue block to the Histopathology Section, Department of Pathology, SGH. If sending slide sections, send at least 8 sections of 8 micrometres thickness, or at least 20 sections of 5 micrometres thickness. One H&E slide, 4 micrometre thick, with a coverslip as a reference slide for the unstained slides, must also be included.

Storage and Transport

​Not applicable

Method

​PCR (using BIOMED-2 primer sets) and fragment analysis

Test Results

​Clonality detected, Polyclonality detected, No clonality detected, Inconclusive

Reference Interval / Value

Turnaround Time

​8 days

Day(s) Test Set up

​Monday and Wednesday

Remarks

Change History Notes

Others

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