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SARS-CORONAVIRUS (SARS-COV) ANTIBODY

Synonym(s):

SARS Total Ab, SARS IgM Ab, SARS IgG Ab

Lab Section Category

Description

​SARS-CoV IgM (anti-SARS IgM)

SARS-CoV IgG (anti-SARS IgG)

SARS-CoV Total Antibody (anti-SARS total)

Indications

Specimen Required

​6 – 8 mL plain blood in acute infection; 3 – 5 mL plain blood to diagnose past infection.

(a) To diagnose acute SARS, send acute sample for IgM and total antibody, and a second sample two to three weeks later for IgM, IgG and total antibody.

(b) To diagnose past infection, send one sample for IgG antibody.

Storage and Transport

​Refrigerate samples if delay in transporting to laboratory is anticipated. Do not freeze.

Method

​Anti-SARS IgM: Immunofluorescence assay

Anti-SARS IgG: Immunofluorescence assay

Anti-SARS total: Enzyme Immunoassay

Test Results

Acute infection: SARS IgM positive and confirmed by ≥ 4 fold rise of total Ab titres in paired sera or IgG seroconversion.

Past infection: SARS IgG positive

Reference Interval / Value

Turnaround Time

​Anti-SARS IgM or IgG : <1 – 4 days

Anti-SARS total : 3 – 8 days

Day(s) Test Set up

​Anti-SARS IgM : Tuesday and Friday

Anti-SARS IgG : Tuesday and Friday

Anti-SARS total : Friday

Remarks

Change History Notes

  • 17 May 2018 03:40 PM

    Changed TAT for Anti-SARS Total Antibody test to 3 - 8 days.

Others

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