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METHOTREXATE, SERUM

Synonym(s):

Lab Section Category

Description

Indications

Specimen Required

​3 mL plain blood

Storage and Transport

Method

​Immunoassay

Test Results

Reference Interval / Value

​Therapeutic levels vary with specific treatment protocols and/or guidelines.
From literature review, the following values are predictive for the development of toxicity after high-dose therapy:
Methotrexate >5-10 µmol/L 24 hours after dose
Methotrexate >1.0 µmol/L 48 hours after dose
Methotrexate >0.1 µmol/L 72 hours after dose
Please correlate clinically.

Turnaround Time

​Mean = 4 hrs, Range 3 – 5 hrs

Day(s) Test Set up

​Daily

Remarks

Change History Notes

Others

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