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MEASLES ANTIBODY

Synonym(s):

​Measles Virus IgM Ab, Measles Virus IgG Ab, Measles Total Ab, Measles CF Ab

Lab Section Category

Description

​Measles IgM or IgG Antibody (anti-Measles IgM or IgG)

Measles Total CF Antibody (anti-Measles total)

Indications

Specimen Required

​3 – 5 mL plain blood.

(a) To diagnose acute measles infection, send single acute sample for IgM antibody and a second serum taken two weeks later for measles total CF antibody on the pair.

(b) To diagnose past infection, send single sample for IgG antibody.

Storage and Transport

​Refrigerate samples if delay in transporting to laboratory is anticipated. Do not freeze.

Method

​Anti-Measles IgM: Enzyme Immunoassay

Anti-Measles IgG: Immunofluorescence assay

Anti-Measles total: Complement Fixation Test

Test Results

Acute infection: Acute serum positive for IgM and/or paired sera showing ≥ 4 fold rise in CF Ab titres

Past infection/Immunity: Presence of IgG Ab in the absence of specific IgM

Reference Interval / Value

Turnaround Time

​Anti-Measles IgM: <1 – 4 days

Anti-Measles IgG: <1 – 4 days

Anti-Measles Total: 1 – 6 days

Day(s) Test Set up

​Anti-Measles IgM: Tuesday and Friday Anti-Measles IgG: Tuesday and Friday Anti-Measles Total: Tuesday and Thursday

Remarks

Change History Notes

Others

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