Measles Virus IgM Ab, Measles Virus IgG Ab, Measles Total Ab, Measles CF Ab
Measles IgM or IgG Antibody (anti-Measles IgM or IgG) Measles Total CF Antibody (anti-Measles total)
3 – 5 mL plain blood. (a) To diagnose acute measles infection, send single acute sample for IgM antibody and a second serum taken two weeks later for measles total CF antibody on the pair. (b) To diagnose past infection, send single sample for IgG antibody.
Refrigerate samples if delay in transporting to laboratory is anticipated. Do not freeze.
Anti-Measles IgM: Enzyme Immunoassay Anti-Measles IgG: Immunofluorescence assay Anti-Measles total: Complement Fixation Test
Acute infection: Acute serum positive for IgM and/or paired sera showing ≥ 4 fold rise in CF Ab titres Past infection/Immunity: Presence of IgG Ab in the absence of specific IgM
Anti-Measles IgM: <1 – 4 days Anti-Measles IgG: <1 – 4 days Anti-Measles Total: 1 – 6 days
Anti-Measles IgM: Tuesday and Friday
Anti-Measles IgG: Tuesday and Friday
Anti-Measles Total: Tuesday and Thursday
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