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ITRACONAZOLES, SERUM

Synonym(s):

Lab Section Category

Description

Indications

Specimen Required

​3 mL plain blood in red top tube (no gel)

Blood sample should be taken just before the next dose for assessment of trough level.

Storage and Transport

Method

​High Performance Liquid Chromatography

Test Results

Reference Interval / Value

​Therapeutic Range:
Suggested total trough level
(Itraconazole + Hydroxy-Itraconazole): > 1.5 mg/L
(Clin Infect Dis 2016; 63: e1 - 60)

Turnaround Time

​Mean = 3 days, Range: 2 - 5 days

Day(s) Test Set up

​Tuesday and Friday

Remarks

Measured Parameters: Itraconazole, Hydroxy-Itraconazole
Reported Parameters: Itraconazole, Hydroxy-Itraconazole, Total Itraconazole
Total Itraconazole is calculated from the sum of Itraconazole and Hydroxy-Itraconazole.


Patient Preparation:

Patient should abstain from the following at least 3 days prior to and during blood sample collection:
- where medically possible, drugs such as Amprevavir, Valsartan.

The list of drugs have been selected on the basis of potential significance to test measurement and are not necessarily all-inclusive.

Please contact the Clinical Biochemistry Laboratory for assistance if necessary.

Change History Notes

Others

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