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GLOMERULAR FILTRATION RATE, ESTIMATED, PROFILE

Synonym(s):

Lab Section Category

Description

Indications

​Estimated Glomerular Filtration Rate (eGFR) results are reported based on the following available options in SGH:

1. Cockcroft-Gault equation (normalised for standard body surface area of 1.73 m2)

2. Modification of Diet in Renal Disease (MDRD) equation

3. Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) Equation

Specimen Required

​3 mL plain blood.

Required parameters:

1. For Cockcroft-Gault Equation: Serum Creatinine (µmol/L), weight (kg), height (cm), age (years), gender

2. For MDRD Equation: Serum Creatinine (µmol/L), age (years), gender

3. For CKD-EPI Equation: Serum Creatinine (µmol/L), age (years), gender

Storage and Transport

Method

Test Results

Reference Interval / Value

Classification of Chronic Kidney Disease based on NKF Kidney Disease Outcome Quality Initiative (KDOQI):


 Stage 1. Normal GFR >90ml/min/1.73 m2

Stage 2. Mildly impaired GFR 60-89ml/min/1.73 m2

Stage 3. Moderately impaired GFR 30-59 ml/min/1.73 m2

Stage 4. Severely impaired GFR 15-29 ml/min/1.73 m2

Stage 5. Established renal failure <15ml/min/1.73 m2

Turnaround Time

​Mean = 4 hrs, Range: 3 – 5 hrs

Day(s) Test Set up

​Daily

Remarks

​Lab Measured Parameter: Creatinine (serum)

Cockcroft-Gault, MDRD, CKD-EPI equation option(s) must be clearly indicated on laboratory requests for estimated Glomerular Filtration Rate (eGFR).

Change History Notes

  • 21 Jan 2015 09:50 AM

    New MDRD equation option available w.e.f 19 Jan 2015

  • 03 Oct 2016 10:40 AM

    New CKD-EPI equation option available w.e.f 03 Oct 2016

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