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EPSTEIN-BARR VIRUS (EBV) ANTIBODY

Synonym(s):

​EBV VCA IgG, EBV VCA IgG Antibody, EBV Viral Capsid Ag IgG, EBV VCA IgM, EBV VCA IgM Antibody, EBV Viral Capsid Ag IgM, EBV Ea IgA, EBV Ea IgA Antibody, EBV Early Antigen IgA, EBV VCA IgA, EBV VCA IgA Antibody, EBV Viral Capsid Ag IgA

Lab Section Category

Description

​Epstein-Barr virus VCA IgM Antibody (anti-VCA IgM)

Epstein-Barr virus VCA IgG Antibody (anti-VCA IgG)

Epstein-Barr virus VCA IgA (anti-VCA IgA) 

Epstein-Barr virus EA IgA (anti-EA IgA)

Indications

Specimen Required

​3 – 5 mL plain blood.

(a) To diagnose acute infection, send single sample for EBV VCA IgM Antibody and second serum taken 10 – 14 days later if indicated.

(b) To diagnose previous infection, send single sample for EBV VCA IgG Antibody.

(c) To screen and aid in the diagnosis of nasopharyngeal carcinoma (NPC), send blood for EBV VCA IgA Antibody and EBV EA IgA Antibody.

Storage and Transport

​Refrigerate samples if delay in transporting to laboratory is anticipated. Do not freeze.

Method

​Immunofluorescence assay

Test Results

Acute infection: EBV VCA IgM positive or paired sera showing seroconversion

Previous (latent) infection: EBV VCA IgG positive

Anti-VCA IgA: Negative or Positive (Titre)

Anti-EA IgA: Negative or Positive (Titre)

Reference Interval / Value

Turnaround Time

​Anti-VCA IgM/IgG : <1 – 4 days

Anti-VCA IgA : <1 - 7 days

Anti-EA IgA : <1 - 7 days

Day(s) Test Set up

​Anti-VCA IgM/IgG : Tuesday and Friday Anti-VCA IgA : Wednesday morning Anti-EA IgA : Wednesday morning

Remarks

Change History Notes

Others

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