Synonym(s):
EBV VCA IgG, EBV VCA IgG Antibody, EBV Viral Capsid Ag IgG, EBV VCA IgM, EBV VCA IgM Antibody, EBV Viral Capsid Ag IgM, EBV Ea IgA, EBV Ea IgA Antibody, EBV Early Antigen IgA, EBV VCA IgA, EBV VCA IgA Antibody, EBV Viral Capsid Ag IgA
Epstein-Barr virus VCA IgM Antibody (anti-VCA IgM) Epstein-Barr virus VCA IgG Antibody (anti-VCA IgG) Epstein-Barr virus VCA IgA (anti-VCA IgA) Epstein-Barr virus EA IgA (anti-EA IgA)
3 – 5 mL plain blood. (a) To diagnose acute infection, send single sample for EBV VCA IgM Antibody and second serum taken 10 – 14 days later if indicated. (b) To diagnose previous infection, send single sample for EBV VCA IgG Antibody. (c) To screen and aid in the diagnosis of nasopharyngeal carcinoma (NPC), send blood for EBV VCA IgA Antibody and EBV EA IgA Antibody.
Refrigerate samples if delay in transporting to laboratory is anticipated. Do not freeze.
Immunofluorescence assay
Acute infection: EBV VCA IgM positive or paired sera showing seroconversion Previous (latent) infection: EBV VCA IgG positiveAnti-VCA IgA: Negative or Positive (Titre) Anti-EA IgA: Negative or Positive (Titre)
Anti-VCA IgM/IgG : <1 – 4 days Anti-VCA IgA : <1 - 7 days Anti-EA IgA : <1 - 7 days
Anti-VCA IgM/IgG : Tuesday and Friday Anti-VCA IgA : Wednesday morning Anti-EA IgA : Wednesday morning
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