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DENGUE VIRUS ANTIBODY

Synonym(s):

​Dengue IgM, Dengue IgG

Lab Section Category

Description

​Dengue IgM antibody (anti-Dengue IgM)

Dengue IgG antibody (anti-Dengue IgG)

Indications

Specimen Required

​3 – 5 mL plain blood.

To diagnose acute infection, send acute sample for dengue IgM antibody and if necessary, a second sample taken 7 – 10 days later for dengue IgM on the pair.

To identify previous exposure to dengue virus, please send a sample for dengue IgG. Although seroconversion of dengue IgG on paired samples 7-10 days apart demonstrates acute infection, dengue IgM and dengue NS1 antigen detection are preferred tests for diagnosis.

Storage and Transport

​Refrigerate samples if delay in transporting to laboratory is anticipated. Do not freeze.

Method

​Dengue IgM/ IgG : Enzyme immunoassay

Test Results

Acute infection: IgM antibody positive on acute serum or paired sera showing seroconversion of IgM and/or IgG

Past infection: Presence of IgG antibody in the absence of specific IgM

Note:  A positive result can be due to cross-reactive flavivirus antibodies and should be correlated clinically.

Reference Interval / Value

Turnaround Time

​Dengue IgM : <1 – 3 days

Dengue IgG : <1 – 7 days

Day(s) Test Set up

​Dengue IgM : Monday, Wednesday and Friday

Dengue IgG : Thursday

Remarks

Change History Notes

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