The purpose of a cytological examination is generally for the cytological detection of malignancy. Cytology laboratory offers screening of cervical-vaginal samples and the interpretation of non-gynecological and fine needle aspiration (FNA) specimens with the ultimate goal of attaining the most accurate and complete diagnosis possible.
The goals of the service include:
Services provided by the laboratory include:
Other services available :
Please refer to following sections for site specific collection instructions:
(A) Gynaecological Cytology(B) Non-Gynaecological - Smear, Fluid and Fine Needle Aspiration (FNA)(C) BAL differential cell count and sputum cell count(D) Demodex detection in eyelashes
(A) Gynaecological Cytology
(B) Non-Gynaecological - Smear, Fluid and Fine Needle Aspiration (FNA)
(C) BAL differential cell count and sputum cell count
(D) Demodex detection in eyelashes
The cervical (Pap) smear is a screening technique to aid in the detection of cancer and cancer precursors of the uterine cervix. It is not a diagnostic procedure. Both false-negative and rarely, false-positive results have been experienced with Pap smears. Accordingly, any lesion detected on screening should be biopsied. The Pap smear should not be used as the sole means to diagnose or exclude malignant and premalignant lesions. Cytology lab accepts liquid based (ThinPrep) and conventional pap smears.
With effect from 7 September 2016, all specimens are to be submitted with CPOE requests and labelled with their respective CPOE labels. Ordering clinicians are reminded to save the order at the end of entry to ensure proper submission of the CPOE request. Submit one request for the same patient at the same operation, irrespective of the number of specimens taken. In the event that CPOE system is not available, test request forms should be submitted. The request must include:
It is imperative that these instructions be strictly adhered to, omission of which may result in delay of reporting.
Broom-Like Device Protocol - extracted from Hologic Publication
Note: Under no circumstances should the speculum be lubricated with medical jelly as it can make the Pap test unsatisfactory.
Endocervical Brush/ Spatula Protocol - extracted from Hologic Publication
Note: Under no circumstances should the collection device be lubricated as it can make the Pap test unsatisfactory.
A satisfactory liquid-based ThinPrep preparation should show a minimum of 5,000 well-visualized/preserved squamous cells. If fewer than these are seen because of paucity of cells, poor fixation, air-drying artefact, thick smearing, or covering of blood, inflammatory exudate (with >75% of cells obscured) or other contaminants, the smear is considered unsatisfactory. A smear comprising mainly endocervical cells is also considered unsatisfactory, unless the smear was intended to specifically evaluate the endocervical canal.
With effect from 7 September 2016, all specimens are to be submitted with CPOE requests and are to be labelled with their respective CPOE labels. Submit one request for the same patient at the same procedure, irrespective of the number of specimens taken. Ordering clinicians are reminded to check the following boxes before submission:
In the event that CPOE order is not available, hardcopy histopathological investigation request forms should be submitted. The request forms must include:
Specimens that require urgent reporting should be delivered immediately by hand to the cytology laboratory. The request should be indicated in the CPOE request.
If there is an additional test (e.g.: immunocytochemistry, molecular, FISH) to be done after a case has been reported, a new CPOE request has to be submitted. The respective CPOE label has to be sent to the laboratory. The request must include: