Mumps Virus IgG, Mumps Virus IgM, Mumps Virus Total Ab
Mumps IgM or IgG Mumps Total Antibody
3 – 5 mL plain blood. (a) To diagnose acute infection, send single acute sample for mumps IgM and a second serum taken two weeks later for mumps total antibody. (b) To diagnose past infection or for evidence of immunity, send single sample for mumps IgG.
Refrigerate samples if delay in transporting to laboratory is anticipated. Do not freeze.
Mumps IgM : Immunofluorescence assay (IFA)
Mumps IgG : Enzyme immunoassay (EIA)
Mumps total Ab : Complement Fixation Test (CFT)
Acute infection : Acute serum positive for IgM. A negative IgM result within 5 days of onset of illness should be repeated +/- send convalescent sample for total Ab (a ≥ 4x rise in titre will confirm acute infection). Past infection/Immunity : Presence of IgG in the absence of specific IgM
Mumps IgM : <1 – 4 days
Mumps IgG : <1 - 7 days
Mumps Total Ab : 1 – 6 days
Mumps IgM : Tuesday and Friday
Mumps IgG : Thursday
Mumps Total Ab : Tuesday and Thursday