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MUMPS ANTIBODY

Synonym(s):

​Mumps Virus IgG, Mumps Virus IgM, Mumps Virus Total Ab

Lab Section Category

Description

​Mumps IgM or IgG 

Mumps Total Antibody

Indications

Specimen Required

​3 – 5 mL plain blood.

(a) To diagnose acute infection, send single acute sample for mumps IgM and a second serum taken two weeks later for mumps total antibody.

(b) To diagnose past infection or for evidence of immunity, send single sample for mumps IgG.

Storage and Transport

​Refrigerate samples if delay in transporting to laboratory is anticipated. Do not freeze.

Method

​Mumps IgM : Immunofluorescence assay (IFA)

Mumps IgG : Enzyme immunoassay (EIA)

Mumps total Ab : Complement Fixation Test (CFT)

Test Results

Acute infection : Acute serum positive for IgM. A negative IgM result within 5 days of onset of illness should be repeated +/- send convalescent sample for total Ab (a ≥ 4x rise in titre will confirm acute infection). 

Past infection/Immunity : Presence of IgG in the absence of specific IgM

Reference Interval / Value

Turnaround Time

​Mumps IgM : <1 – 4 days

Mumps IgG : <1 - 7 days

Mumps Total Ab : 1 – 6 days

Day(s) Test Set up

​Mumps IgM : Tuesday and Friday

Mumps IgG : Thursday

Mumps Total Ab : Tuesday and Thursday

Remarks

Change History Notes

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