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MEASLES ANTIBODY

Synonym(s):

​Measles Virus IgM, Measles Virus IgG, Measles Virus Total Ab

Lab Section Category

Description

​Measles IgM or IgG Antibody 

Measles Total Antibody

Indications

Specimen Required

​3 – 5 mL plain blood.

(a) To diagnose acute measles infection, send single acute sample for measles IgM and a second serum taken two weeks later for measles total antibody.

(b) To diagnose past infection or for evidence of immunity, send single sample for measles IgG.

Storage and Transport

​Refrigerate samples if delay in transporting to laboratory is anticipated. Do not freeze.

Method

Measles IgM : Enzyme Immunoassay (EIA) 

Measles IgG : Enzyme Immunoassay (EIA)

 Measles total Ab : Complement Fixation Test (CFT) 

Test Results

Acute infection : Acute serum positive for IgM. A negative IgM result within 5 days of onset of illness should be repeated +/- send convalescent sample for total Ab (a ≥ 4x rise in titre will confirm acute infection). 

Past infection/Immunity : Presence of IgG in the absence of specific IgM

Reference Interval / Value

Turnaround Time

​Measles IgM : <1 – 4 days 

Measles IgG : <1 – 7 days 

Measles Total Ab : 1 – 6 days

Day(s) Test Set up

​Measles IgM : Tuesday and Friday

Measles IgG : Thursday

Measles Total Ab : Tuesday and Thursday

Remarks

Change History Notes

Others

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