3 mL plain blood in red top tube (no gel)
Blood sample should be taken just before the next dose for assessment of trough level.
High Performance Liquid Chromatography
Therapeutic Range: Suggested total trough level (Itraconazole + Hydroxy-Itraconazole): > 1.5 mg/L (Clin Infect Dis 2016; 63: e1 - 60)
Mean = 3 days, Range: 2 - 5 days
Tuesday and Friday
Measured Parameters: Itraconazole, Hydroxy-ItraconazoleReported Parameters: Itraconazole, Hydroxy-Itraconazole, Total ItraconazoleTotal Itraconazole is calculated from the sum of Itraconazole and Hydroxy-Itraconazole.
Patient should abstain from the following at least 3 days prior to and during blood sample collection:- where medically possible, drugs such as Amprevavir, Valsartan.
The list of drugs have been selected on the basis of potential significance to test measurement and are not necessarily all-inclusive.
Please contact the Clinical Biochemistry Laboratory for assistance if necessary.