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​EBV VCA IgG, EBV VCA IgG Antibody, EBV Viral Capsid Ag IgG, EBV VCA IgM, EBV VCA IgM Antibody, EBV Viral Capsid Ag IgM, EBV Ea IgA, EBV Ea IgA Antibody, EBV Early Antigen IgA, EBV VCA IgA, EBV VCA IgA Antibody, EBV Viral Capsid Ag IgA

Lab Section Category


​Epstein-Barr virus VCA IgM

Epstein-Barr virus VCA IgG

Epstein-Barr virus VCA IgA 

Epstein-Barr virus EA IgA


Specimen Required

​3 – 5 mL plain blood.

(a) To diagnose acute infection, send single sample for EBV VCA IgM and second serum taken 10 – 14 days later if indicated.

(b) To diagnose previous infection, send single sample for EBV VCA IgG.

(c) To screen and aid in the diagnosis of nasopharyngeal carcinoma (NPC), send blood for EBV VCA IgA and EBV EA IgA.

Storage and Transport

​Refrigerate samples if delay in transporting to laboratory is anticipated. Do not freeze.


​EBV VCA IgM & IgG: Chemiluminescent Microparticle Immunoassay

EBV VCA IgA & EA IgA: Immunofluorescence assay

Test Results

Acute infection: EBV VCA IgM positive or paired sera showing seroconversion

Previous (latent) infection: EBV VCA IgG positive

EBV VCA IgA: Negative or Positive (Titre)

EBV EA IgA: Negative or Positive (Titre)

Reference Interval / Value

Turnaround Time

​EBV VCA IgM/IgG : <1 – 4 days

EBV VCA IgA : <1 - 7 days

EBV EA IgA : <1 - 7 days

Day(s) Test Set up

​EBV VCA IgM/IgG : Tuesday and Friday

EBV VCA IgA : Wednesday morning

EBV EA IgA : Wednesday morning


Change History Notes



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