Upper abdominal pain / discomfort or dyspepsia may be due to conditions affecting oesophagus, stomach, duodenum, gallbladder, bile duct, liver or pancreas. Dyspepsia is not typically related to intake of food.
When accompanied by other features such as nausea, weight loss, lethargy, jaundice etc., alarm should be raised, and referral for expedient work-up be made. Infrequently, the colon, abdominal aorta or spine may be the site of pathology. From the clinical history, the likely cause of pain is usually apparent, such as a bleeding ulcer or gallstones flatulence.