Research Urology

​

Beyond providing clinical services to cover a wide spectrum of urological conditions, the department also has strong endeavors in research, contributing to the body of knowledge in the field. This comprises of several grant-supported clinical trials as well as research harnessing the strengths of our robust prospectively maintained cancer registry and database.

Current ongoing clinical trials:

• Multi-Cancer Early Detection (MCED) Study - Clinical study evaluating accuracy and reliability of urine test to diagnose early kidney, bladder, and prostate cancer
• FLAME-PC (Focal therapy or radical therapy: Lesion-based Molecular Evaluation in Prostate Cancer)
• Prospective Asian Multicenter Prostate Cancer Focal Therapy Study (ProAMFocal)
• A Prognostic and Predictive Clinical-Molecular Signature for Risk-stratification of Localized Prostate Cancer
• Evaluating functional and oncological outcomes of Focal Cryotherapy for Prostate Cancer using a Novel MRI-US fusion robotic platform: A Prospective Study
• WeeCare – Creation of a novel device for personalized assessment of patients with lower urinary tract symptoms (LUTS)
• Management of Detrusor-overactivity with Detrusor-underactivity (DO-DU) via Stimulation of the Tibial nerve – the MODEST pilot study
• Targeting pressure transmission to the bladder in stress urinary incontinence.
• MV140 Vaccine for Prevention of Urinary Tract Infections in the Presence of a Foreign Body
• Analysis of Bladder Imaging Software for Overactive bladder
• Creation of a novel Audio Uroflow App for use with a smart phone for the assessment of patients with lower urinary tract symptoms
• Generation of bladder cancer PDX in humanized mice and its use in drug testing
• A non-interventional study of efficacy and utility of BC101 urine test for diagnosis of urothelial cancer
• Development and Validation of Novel Point of Care Urine Biochemistry Device to Optimize Management of Nocturia
• AI in Cytopathology of Bladder Cancer

Recent department publications: