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VARICELLA ZOSTER VIRUS (VZV) ANTIBODY

Synonym(s):
Lab Section Category
Test Description

​VZV IgM 

VZV IgG 

VZV IgG (Rapid)

Specimen Required

​3 – 5 mL plain blood.

(a) To diagnose acute varicella infection, send single acute sample for VZV IgM.

(b) To diagnose past infection or immunity, send single sample for VZV IgG.

(c) For urgent screening for immunity after exposure, send sample for VZV IgG (Rapid).

Storage/Transport

​Refrigerate samples if delay in transporting to laboratory is anticipated. Do not freeze.

Method

​VZV IgM : Immunofluorescence assay (IFA)

VZV IgG : Enzyme Immunoassay (EIA)

VZV IgG (Rapid) (for urgent testing only) : Enzyme linked fluorescence assay (ELFA)

Test Results

Acute infection: Single sample positive for VZV IgM.

Immunity: VZV IgG present

VZV IgG (EIA): The test(s) carries an international registration mark (non-HSA) and is used in accordance to laboratory accreditation guidelines.

Turnaround Time

Urgent cases
VZV IgM : 3 – 4 hrs 
VZV IgG (Rapid) : 1 – 48 hrs

Routine cases
VZV IgM : <1 – 4 days 
VZV IgG : <1 – 7 days 

Day(s) Test Set up

​VZV IgM/IgG (Rapid) : Stat for urgent cases

VZV IgM : Tuesday and Friday

VZV IgG : Thursday

Change History Notes

  • 01 Sep 2025 12:00 AM

    Discontinued Varicella Zoster Virus Total Antibody test w.e.f 01 September 2025.

  • 13 Aug 2024 12:00 AM

    ​Added result comment to the VZV IgG (EIA) test.


  • 31 Jul 2021 12:00 AM

    ​Changed day test set up of VZV IgG test.

  • 25 Oct 2019 02:00 PM

    ​Changed Anti-VZV (Rapid) TAT to 1 - 48 hrs.

Back: Pathology Laboratory Services

Last Updated - 06 Oct 2025