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HUMAN PAPILLOMAVIRUS (HPV) HIGH RISK AND HPV 16/18 GENOTYPING

Synonym(s):
Lab Section Category
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Specimen Required

​Cervical specimens should be collected in ThinPrep® PreservCyt® Solution (Hologic Corp.) Follow the manufacturer's instructions for collecting cervical specimens.

Indications

​(a) Used in screening patients with ASC-US (atypical squamous cells of undetermined significance) Pap test results to determine the need for referral to colposcopy.

(b) Used as a first-line primary screening test, with or without cervical cytology, to identify women at increased risk for the development of cervical cancer or presence of high-grade disease, as well as to assess for the presence or absence of HPV types 16 and 18. This information, together with the physician’s assessment of the patient’s screening history, other risk factors, and professional guidelines, may be used to guide patient management.

Storage/Transport

​Samples can be stored at 2-30°C and transported to our laboratory within 1 week after collection.

Method

Multiplex real-time polymerase chain reaction (PCR) using cobas HPV on the Roche cobas 5800/6800 systems. The test specifically identifies human papillomavirus (HPV) types HPV16 and HPV18 and concurrently detects the rest of the 12 high risk HPV types (31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66 and 68).

Turnaround Time

​1-8 days

Day(s) Test Set up

Tuesday and Thursday

Change History Notes

  • 27 Nov 2025 08:09 AM

    Change in method

  • 05 Feb 2021 04:00 PM

    Turnaround Time has been last updated on 05/02/21.

  • 29 Apr 2015 02:45 PM

    Turnaround Time: Turnaround Time has been last updated on 29/04/15.

  • 01 Nov 2013 04:25 PM

    New test available w.e.f. 11 Nov 2013.

    Title: Title has been updated w.e.f. 21 Mar 2014.

Back: Pathology Laboratory Services

Last Updated - 27 Nov 2025