CHROMOSOME ANALYSIS OF FETAL CORD BLOOD/NEONATE BLOOD

Lab Section Category	Cytogenetics – Prenatal View write-up
Specimen Required	Fetal cord blood/neonate blood (2 – 3ml) in sodium/lithium heparin. Invert gently several times to mix the blood and vial contents immediately to prevent clotting (clotted blood will not work). Do not use EDTA or plain tubes.
Indications	- Abnormal ultrasound findings - Neonate with multiple congenital abnormalities - High risk non-invasive prenatal test (NIPT)
Test Results	Normal or Abnormal. If Abnormal, the karyotypic abnormality is described in accordance to the International System for Human Cytogenomic Nomenclature (ISCN, 2024).
Turnaround Time	Preliminary Result: within 3 days Final Result: 6 ~ 7 days
Day(s) Test Set up	Monday – Saturday (office hours)
Remarks	Indicate clearly the clinical diagnosis or ultrasound findings on the cytogenetics request form or CPOE. Do not despatch a specimen near a weekend or a public holiday to avoid unnecessary delays.

Change History Notes

21 Oct 2025 11:07 AM

Updated test results for ISCN, 2020 to ISCN, 2024
24 Mar 2022 02:55 PM

Updated Indications: to include high risk non-invasive prenatal test (NIPT)
and the test result for ISCN, 2016 to ISCN, 2020
06 Jul 2017 10:55 AM

Updated the test result for ISCN, 2013 to ISCN, 2016
08 Dec 2015 08:40 AM

Updated Turnaround Time:
- Preliminary Result: within 3 days
- Final Result: 6 ~ 7 days

Last Updated - 21 Oct 2025