Dr Cai Jiashen

Dr Cai Jiashen obtained his Doctor of Medicine (MD) from Duke-NUS Medical School in 2017. In 2021, he was awarded the Membership of the Royal College of Physicians (MRCP, United Kingdom) and the Master of Internal Medicine (MMed (IM), Singapore). He subsequently completed his Senior Residency Training at SingHealth and was conferred Specialist Accreditation in Renal Medicine by the Ministry of Health, Singapore in 2025. His research focuses on chronic kidney disease, cardiovascular-kidney-metabolic health, and healthcare utilisation, with interest in risk prediction, patient outcomes, and clinical optimisation. He applies data-driven and digital approaches to support decision-making and improve nephrology care.

• BEng (Hons)
• MD (Duke-NUS, Singapore)
• USMLE, ECFMG
• MRCP (UK)
• MMed (IM)
• ESENeph (UK/EU)
• Specialist Accreditation in Renal Medicine (Singapore)

• Member, Singapore Society of Nephrology

• Best Poster (Clinical Research - Senior), SingHealth Duke-NUS Scientific Congress (2023)
• Most Outstanding Clinical Science Research Thesis, Duke-NUS Achievement Prize (2017)
• AM-ETHOS Learning Enhancement And Progress (LEAP) Research Award - Excellence (2017)
• Best Poster Presentation, Duke-NUS Poster Day (2016)
• AM-ETHOS Duke-NUS Medical Student Research Fellowship (2016)

• Cardiovascular–Kidney–Metabolic Health
• Chronic Kidney Disease (CKD)
• Hemodialysis

Journal Publications

• Cai J, Kwek JL, Kadir HBA, Tan NC, Ang A, Choo J, Tan CS, Lim C. Impact of the 2021 Chronic Kidney Disease Epidemiology Collaboration glomerular filtration rate estimating equation on risk of healthcare utilization for hospitalizations for cardiovascular and kidney disease. Nephron. 2025. Aug 4:1-20
• Kog Z*, Cai J*, Ng LC, Huang Z, Loo F, Kadir HBA, Kwek JL, Choo J, Choong L, Tan CS, Lim C. Hospital readmissions for all-causes and fluid overload in severely reduced kidney function not requiring dialysis – a retrospective cohort study. Nephrology. 2025; 30(7):e70071 (*Co-first authors)
• Debajyoti R, Cai J, Ng CY,  Koduri S,  Chionh CY,  Sultana R,  Yeon WX. Impact of Type 2 Diabetes Mellitus and Chronic Kidney Disease on Bone Mineral Density in Elderly Patients With Fragility Hip Fracture: A Cross-Sectional Study, Aging Med. 2025. 8(4):279-285
• Tan S, Fong N, Cai J, Debajyoti R. Recurrent Acute Kidney Injury Due to Atheroembolic Renal Disease: Diagnostic Utility of Fundoscopy. Cureus. 2025. 17(9), p. e91523.
• Cai J, Huang D, Kadir HBA, Huang Z, Ng LC, Ang A, Tan NC, Bee YM, Tay WY, Tan CS, Lim C. Hospital readmissions for fluid overload among individuals with diabetes and diabetic kidney disease. Nephron. 2024; 148 (8): 523-535
• Cai J, Chong CCY, Cheng CY, Lim C, Sabanayagam C. Circulating metabolites andcardiovascular disease in Asians with chronic kidney disease. Cardiorenal Med. 2023; 13(1): 301–309
• Cai J, Lim C, Tan HZ, Choo J, Tan PH. Hematuria, proteinuria and renal insufficiency in metastatic prostate cancer. Kidney International. 2022;102(4): 945-946
• Cai J, Loh A, Mok I, Lim C. Herbal supplement and granulomatous acute interstitial nephritis. Saudi J Kidney Dis Transpl. 2021; 32: 1182
• Meyer H, Dawes T, Serrani M, Bai W, Tokarczuk P, Cai J, et al. Genetic and functionalinsights into the fractal structure of the heart. Nature. 2020; 584(7822): 589–594
• Pua CJ, Tham N, Chin C, Walsh R, Chien C, Toepfer C, Repetti G, Garfinkel A, Ewoldt J, Chen C, Lim SQ, Cai J, et. al. Genetic studies of hypertrophic cardiomyopathy in Singaporeans identify variants in TNNI3 and TNNT2 that are common in Chinese patients. Circ Genom Precis Med. 2020; 13(5): 424–434
• Dawes T, Cai J, Quinlan M, Marvao A, Ostrowski P, Tokarczuk P, Watson G, Wharton J, Howard L, Gibbs J, Cook SA, Wilkins M, O’Regan D. Fractal analysis of right ventricular trabeculae in pulmonary hypertension. Radiology. 2018; 288(2): 386–395
• Cai J, Bryant J, Le T, Su B, Marvao A, O’Regan D, Cook SA, Chin C. Fractal analysis of left ventricular trabeculations is associated with impaired myocardial deformation in healthy Chinese. J Cardiovasc Magn Reson. 2017; 19(1): 102

Book Chapters

• Cai J, Kwek JL. Sodium Disorders. In: The Kidney Book. 2023, p.47-56
• Cai J, Htay H. Peritoneal-dialysis related Peritonitis. In: The Kidney Book. 2023, p.459-469
• Cai J, Lalmalani RM. Polyuric syndrome. In: The Geriatric Admission: A Handbook for Hospitalist. 2023, p. 219-227