Assoc Prof Lynette Oon

A/Prof Lynette Oon is a Senior Consultant clinical microbiologist with a special interest in molecular microbiology. She is currently Head of the Department of Microbiology in the Singapore General Hospital and also holds the position of Clinical Associate Professor at the Duke-NUS Medical School. She was the first Head of the Molecular Laboratory Section in the Department of Microbiology in the Singapore General Hospital from 2006-2025 where she helped to develop its range of molecular tests in microbiology, detection of mutations in somatic cancers as well as pharmacogenomics molecular tests. She was Head of the Department of Molecular Pathology, Singapore General Hospital from 2016-2023 when she led the department to respond to the COVID-19 pandemic and was Academic Vice-Chair (Clinical Quality and Innovation) in the Pathology Academic Clinical Programme, SingHealth Duke-NUS Academic Medical Centre from 2017-2023. In addition to her duties in the field of clinical microbiology, she is actively involved in the field of biological safety. She is the Director of the SingHealth Office of Biosafety and chairs the SingHealth Institutional Biosafety Committee which oversees biological safety in research within SingHealth.

• ​1989 BSc Degree (First Class Honours) in Pathology (Royal Free Hospital School of Medicine, University of London) 
• 1992 MBBS Degree (Royal Free Hospital School of Medicine, University of London) 
  
• 1995 MRCP (Royal College of Physicians, United Kingdom) 
  
• 2001 FRCPA (Royal College of Pathologists of Australasia) 
  
• 2001 Specialist Accreditation in Pathology with Ministry of Health and Singapore Medical Council 
  

• Senior Consultant and Head, Department of Microbiology, Singapore General Hospital 
  
• Clinical Associate Professor, Duke-NUS Medical School 
  
• Director, SingHealth Office of Biosafety
  
• Chairman, SingHealth Institutional Biosafety Committee
  

• Oon LLE, King A, Higgins JA, Lee CA, Kernoff PBA, Goodall AH. Protective antibodies to hepatitis B virus in haemophiliacs. Journal of Medical Virology 1991; 33: 19-25. 
  
• Oon LLE, Ling ML, Chiew YF. Gastrointestinal colonisation of vancomycin-resistant enterococcus in a Singapore teaching hospital. Pathology 2001; 33: 216-221. 
  
• Oon LLE and Yeo MGC. Fluconazole Susceptibility of Candida Species in Singapore by Disc Diffusion Test. Annals Academy of Medicine Singapore 2002; 31:497-501. 
  
• Oon LLE and Ling AE. Enterovirus infection: overview and laboratory diagnosis.In: Lin RVTP and Goh KT, eds. Enterovirus Infection in Singapore. Institute of Environmental Epidemiology, Ministry of the Environment, Singapore; 2002:46- 65. 
  
• Ruan YiJun, Chia Lin Wei, Ling Ai Ee, Vinsensius B Vega, Herve Thoreau, Se Thoe Su Yun, Jer-Ming Chia, Patrick Ng, Kuo Ping Chiu, Landri Lim, Zhang  Tao, Chan Kwai Peng, Lynette Oon Lin Ean, Ng Mah Lee, Leo Yee Sin, Lisa F Ng, Ren Ee Chee, Lawrence W Stanton, Philip M Long, Edison T Liu.  Comparative full-length genome sequence analysis of 14 SARS coronavirus  isolates and common mutations associated with putative origins of infection.  Lancet 2003; 361:1779-85. 
  
• Yao JD, Beld MG, Oon LL, Sherlock CH, Germer J, Menting et al. Multicenter evaluation of the VERSANT hepatitis B virus DNS 3.0 assay. Journal of Clinical Microbiology 2004; 42(2):800-6. 
  
• Thuan Tong Tan, Ban Hock Tan, Asok Kurup, Lynette Lin Ean Oon, Derrick Heng, Su Yun Se Thoe, XinLai Bai, Kwai Peng Chan, Ai Ee Ling. Atypical SARS and Escherichia coli Bacteremia. Emerging Infectious Diseases 2004; 10(2):349-352. 
  
• Pek Yoon Chong, Paul Chui, Ai E Ling, Teri J Franks, Dessmon YH Tai, Yee Sin Leo, Gregory JL Kaw, Gervais Wansaicheong, Kwai Peng Chan, Lynette Lin Ean Oon, Eng Swee Teo, Kong Bing Tan, Noriko Nakajima, Tetsutaro Sata, William D Travis. Analysis of Deaths During the Severe Acute Respiratory Syndrome (SARS) Epidemic in Singapore – Challenges in Determining a SARS Diagnosis. Archives of Pathology and Laboratory Medicine 2004; 128:195-204. 
  
• Lim PL, Kurup A, Gopalakrishna G, Chan KP, Wong CW, Ng LC, Se-Thoe SY, Oon L, Bai X, Stanton LW, Ruan Y, Miller LD, Vega VB, James L, Ooi PL, Kai CS, Olsen SJ, Ang B, Leo YS. Laboratory-acquired severe acute respiratory syndrome. N Engl J Med. 2004 Apr 22;350(17):1740-5. 
  
• Kurup Asok; Chlebicka Nidhi; Tan Kwee Yuen; Chen Eileen Xueqin; Oon Lynette; Ling Tan Ai; Ling Moi Lin; Hong Jenny Low Guek. Active surveillance testing and decontamination strategies in intensive care units to reduce methicillin-resistant Staphylococcus aureus infections. American Journal of Infection Control 2010; 38(5):361-377. 
  
• Low Chian Yong; Kee Terence; Chan Kwai Peng; Oon Lynette L E; Tan Chee Kiat; Tee Nancy W S; Tan Ban Hock. Pandemic (H1N1) 2009 infection in adult solid organ transplant recipients in Singapore. Transplantation 2010; 90(9):1016-1212. 
  
• Lim Kun Lee; Eden John-Sebastian; Oon Lynette L E; White Peter A. Molecular epidemiology of norovirus in Singapore, 2004-2011. Journal of Medical Virology 2013; 85(10):1842-1515 
  
• Tay Sun Kuie; Oon Lynette Lin Ean. Prevalence of cervical human papillomavirus infection in healthy women is related to sexual behaviours and educational level: a cross-sectional study. International Journal of STD & AIDS 2014; 25(14):1013-1212 
  
• Oon Lynette L E; Ng Lee Ching. Chikungunya in Singapore--the battle continues. Annals of the Academy of Medicine, Singapore 2014; 43(6):325-377. 
  
• Tan Daniel S-W; Montoya Joey; Ng Quan-Sing; Chan Kian-Sing; Lynette Oon; Sakktee Krisna Sai; Takano Angela; Lim Wan-Teck; Tan Eng-Huat; Lim Kiat-Hon. Molecular profiling for druggable genetic abnormalities in carcinoma of unknown primary. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2013; 31(14):e237-0999