Dr Lionel Raphael Chen Hui

Dr. Lionel Chen is a Consultant Colorectal Surgeon at Singapore General Hospital (SGH) and the National Cancer Centre Singapore (NCCS). He is a Visiting Consultant at KK Women’s and Children’s Hospital, where he is part of a multidisciplinary clinic dedicated to women with functional pelvic floor disorders.

Dr. Chen specializes in advanced minimally invasive techniques and holds full accreditation in both laparoscopic and robotic surgery for the treatment of colorectal diseases.

Dr. Chen is active in clinical research and was awarded the National Medical Research Council Research Training Fellowship (NMRC-RTF) to pursue a PhD in Clinical and Translational Research at Duke-NUS Medical School. His research focuses on the epidemiology and biological mechanisms of early-onset colorectal cancer (EOCRC), a growing problem globally.

• Aug 2022 PhD Candidate at Duke-NUS (Clinical & Translational Research)
• Dec 2020 FRCS (Surgery)
• Oct 2019 MMED (Surgery)
• Jun 2018 ECFMG Certification – Completed USMLE Step 1, 2 CS & CK
• Aug 2014 MRCS (Edinburgh)
• May 2013 MBBS (Singapore)

• 2025 - 4th INEX -OSCAR Award in Translational Research
• 2024 - Long Service Award (10 years)
• 2024 - Singhealth ACP Programme Funding – Nurturing Clinician Scientist Award
• 2023 - SGH Service of the Heart Award 2023
• 2022 - National Medical Research Council Research Training Fellowship
• 2013 - Wu Meng- Chao Young Investigator Award for Best Young Oral Presenter

• Early Onset Colorectal Cancer
• Minimally Invasive and Robotic Surgery for Colorectal Diseases
• Pelvic Floor Disorders

2024 - A study of the genomic, transcriptomic and immunological profiles of early-onset colorectal cancer in Singapore

1. Trends in Early-Onset Colorectal Cancer in Singapore: Epidemiological Study of a Multiethnic Population.
   Chen HLR, Chong QD, Tay B, Zhou S, Wong EYT, Seow-En I, Tan KK, Wang Y, Seow A, Tan KE, Tan BHI, Tan SH.JMIR Public Health Surveill. 2025 Feb 14;11:e62835.
2. The Impact of COVID-19 Pandemic on the Diagnosis, Treatment, and Outcomes of Colorectal Cancer in Singapore.
   Chen HLR, Lee PP, Zhao Y, Ng WHC, Zhao J, Tan YEC, Loh BJS, Chow KP, Tan HK, Tan KE.
   Medicina (Kaunas). 2025 Jan 16;61(1):138.
3. The role of magnetic resonance tumour regression grade in the prediction of regression and survival of rectal adenocarcinoma after long-course chemoradiotherapy: a cohort study.
   Chen HLR, Seow-En I, Chok AY, Ngo NT, Cheng TL, Tan KE.
   Ann Med Surg (Lond). 2023 Apr 3;85(4):842-848.
4. Pouch volvulus after laparoscopic ileal pouch anal anastomosis: the Achilles heel?
   Chen HLR, Chok AY, Cheng TEL, Tan KWE. ANZ J Surg. 2021 Dec 27
5. Impact of multidisciplinary tumour boards (MTB) on the clinicopathological characteristics and outcomes of resected colorectal liver metastases across time
   Chen L, Syn NL, Goh BKP, Cheow PC, Raj P, Koh Y, Chung A, Lee SY, Ooi LL, Chan CY, Teo JY. World J Surg Oncol. 2020 Sep 3;18(1):237