Assoc Prof Apoorva Gogna

MBBS, FRCR, FAMS

Senior Consultant

Singapore General Hospital

Specialty: Diagnostic Radiology

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About

Education and Training

Professional Appointments and Committee Memberships

Awards

Research Interests

Research Trials

Publications

Conditions Treated By This Doctor

Alcohol Sclerotherapy of Benign Thyroid Nodule Bone Pain from Cancer and Percutaneous Treatment Methods Embolisation of Benign Prostate Hyperplasia (BPH) Image-Guided Ablation of Renal Tumours Image-Guided Liver Biopsy Image-Guided Lung Biopsy Malignant Biliary Obstruction Percutaneous Transhepatic Drainage and Stenting Radiofrequency Ablation (RFA) of Benign Thyroid Nodule TIPSS, BRTO and Portal Hypertension Uterine Fibroids Uterine Fibroid Embolisation

Clinical Interests

Interventional Oncology, Vascular and Interventional Radiology

Clinical Appointments

Senior Consultant

Vascular and Interventional Radiology

Visiting Consultant

Department of Cardiac Radiology

Senior Consultant

SingHealth Duke-NUS Vascular Centre

Department of Radiology

Academic Appointments

Clinical Associate Professor, Duke-NUS Medical School

Clinical Lecturer, Yong Loo Lin Medical School, National University of Singapore

Clinical Teacher, Lee Kong Chian Medical School, National Technological University of Singapore

About

Dr Apoorva is Senior Consultant Interventional Radiologist in Singapore General Hospital Department of Vascular and Interventional Radiology, Clinical Associate Professor in Duke-NUS Medical School and Visiting Consultant in several public health institutes.

Dr Apoorva graduated from National University of Singapore Faculty of Medicine and completed basic Radiology training in Singapore. He subsequently received advanced training in Interventional Radiology in USA at the Dotter Interventional Institute in Portland, Oregon, and in the National Cancer Center Hospital in Tokyo Japan.

His main interests are in diagnosis and minimally invasive treatments of cancers, vascular, lymphatic and urogenital disorders. He is principal investigator or co-investigator in several clinical trials and serves as Director for Intervention and Medical Devices Research in SingHealth Academic Clinical Programme. He is recipient of several research grants as detailed below. Received Philanthropic funding for the ACP which enabled the set-up of a collaborative joint grant between Radiological Sciences and Oncology ACPs. Set up the Interventional Radiology Clinical Trials Programme (IR-CTP) via a programme grant from the Singhealth Academic Medicine Ex-Co which was instrumental in supporting over 50 organic projects and collaborations between the Department and other Departments and Institutions.

Education and Training

European Board of Interventional Radiology Certification (EBIR), 2021
HMDP, Advanced Interventional Oncology, National Cancer Center Hospital, Tokyo Japan, 2017
Fellow, Academy of Medicine Singapore (FAMS), 2012
Fellow, Interventional Radiology, Dotter Interventional Institute, OHSU, Portland Oregon, 2010
Fellowship of Royal College of Radiologists (FRCR), 2008
Bachelor of Medicine, Bachelor of Surgery (MBBS), Faculty of Medicine Singapore, 2001

Professional Appointments and Committee Memberships

Director, Intervention and Medical Devices Research, Radiological Science Academic Clinical Programme
Member, SGH Innovation Grant Review Committee
Member, SGH Sustainability Movement Working Group
Member, SGH Hospital Planning Committee

Awards

Long service award - 20 years, 2023
Singapore Health Quality Service Award (Gold), 2022
Best team award: Singhealth Community Care Facility Team, 2021
Magna cum laude, Cardiovascular and Interventional Radiology Society of Europe Meeting, 2021
Cum laude award, Radiological Society of North America Annual Scientific Meeting, 2018
SAF National Service Excellence Award, 2017
Singapore Health Quality Service Award (Gold), 2016
Singapore Health Quality Service Award (Silver), 2015
Best poster award, Image Guided Interventions, 2014
Service with a heart award, 2013
Long Service award - 10 years, 2012
Certificate of merit, American Roentgen Ray Society (ARRS), 2011
SAF Medical Corps appreciation award, 2004
Valedictorian, National University of Singapore Faculty of Medicine, 2001
Bunel Hawes Gold Medal, 2001

Research Interests

Radiation treatments for liver cancer, including intra-arterial radiotherapy and combinations of Y-90 and SBRT
Tissue biopsy for advanced molecular testing
Cost effectiveness and patient reported outcomes
Environmental sustainability in Interventional Radiology

Research Trials

Current trials:

STRATUM trial (Y-90 SIRT in combination with Atezo/Bev systemic therapy), NMRC IAF-ICP Grant funded. Steering committee member, co-I, enrolling
TARTAN trial (TACE and Radiation therapy in HCC), Co-PI, enrolling
SOLSTICE trial (Lung cancer screening), Co-I, enrolling
TRINITY trial (Liver radiation therapy), Co-I, enrolling
IMPRESSION trial (Sirolimus coated balloon for dysfunctional dialysis access treatment), Co-I, enrolling
SEQUILI-H (patient reported outcomes for TACE and Y-90 therapy), completed enrolment

Publications

Selected publications:

Vascular complications related to image-guided percutaneous thermal ablation of hepatic tumors (DOI: 10.5152/dir.2022.21809)
Use of the triple coaxial (triaxial) microcatheter system in superselective arterial embolisation for complex interventional cases: an initial experience with the system (DOI: 10.1186/s42155-022-00340-z)
Complete lymphatic restoration by simultaneous vascularized lymph node and lymphatic vessel
transplantation (DOI: 10.1007/s00238-021-01865-7)
A Randomized Phase 2 Trial of Nivolumab Versus Nivolumab-Ipilimumab Combination in EGFR-Mutant NSCLC (DOI: 10.1016/j.jtocrr.2022.100416)
Radiochemical Feasibility of Mixing of 99mTc-MAA and 90Y-Microspheres with Omnipaque Contrast (DOI: 10.3390/molecules27217646)
Utility of the selution SLR™ sirolimus eluting balloon to rescue failing arterio-venous fistulas - 12 month results of the ISABELLA Registry from Singapore (DOI: 10.1186/s42155-022-00287-1)
Recurrent Stenoses in Arteriovenous Fistula (AVF) for Dialysis Access: cuttIng ballooN angioplaSTy combined wITh paclitaxel drUg-coaTed balloon angioplasty, an observatIONal study (INSTITUTION Study) (DOI: 10.1007/s00270-021-03030-w)
Ranger™ paclitaxel-coated balloon versus conventional balloon angioplasty for treatment of failing arteriovenous fistulas and grafts in haemodialysis patients: A retrospective cohort study (DOI: 10.1177/11297298211067046)
Treatment of cephalic arch stenosis in dysfunctional arteriovenous fistulas with paclitaxel-coated versus conventional balloon angioplasty (DOI: 10.1186/s42155-021-00271-1)
Radioembolisation with Y90-resin microspheres followed by nivolumab for advanced hepatocellular carcinoma (CA 209-678): a single arm, single centre, phase 2 trial (DOI: 10.1016/S2468-1253(21)00305-8)
A Tale of Two Organ Systems: Imaging review of diseases affecting the thoracic and neurological systems (DOI: 10.1067/j.cpradiol.2021.06.008)
Integrative Profiling of T790M-Negative EGFR-Mutated NSCLC Reveals Pervasive Lineage Transition and Therapeutic Opportunities (DOI: 10.1158/1078-0432.CCR-20-4607 )
Individualized Molecular Profiling for Allocation to Clinical Trials Singapore Study-An Asian Tertiary Cancer Center Experience (DOI: 10.1200/PO.20.00261)
Real-World Data on Clinical Outcomes of Patients with Liver Cancer: A Prospective Validation of the National Cancer Centre Singapore Consensus Guidelines for the Management of Hepatocellular Carcinoma (DOI: 10.1159/000514400)
Randomized Controlled Trial Comparing Drug-coated Balloon Angioplasty versus Conventional Balloon Angioplasty for Treating Below-the-Knee Arteries in Critical Limb Ischemia: The SINGA-PACLI Trial (DOI: 10.1148/radiol.2021204294)
Hepatic venous-portal gradient (HVPG) measurement: pearls and pitfalls (DOI: 10.1259/bjr.20210061 )
Systematic Review and Meta-Analysis of Prophylactic Transarterial Embolization for High-Risk Bleeding Peptic Ulcer Disease (DOI: 10.1016/j.jvir.2020.12.005)
Effect of short-term low molecular weight heparin on patency following successful salvage of arteriovenous access with recurrent thrombosis (DOI: 10.1111/nep.13834)
"Angioplasty-First" Approach for Limb Salvage in Asian Patients with Critical Limb Ischemia: Outcomes from 3,303 Angioplasties on 2,402 Limbs in a Single Tertiary Hospital (DOI: 10.1016/j.jvir.2020.08.008 )
Diagnostic Ultrasound Services During the Coronavirus Disease (COVID-19) Pandemic (DOI: 10.2214/AJR.20.23167)
Preparing IR for COVID-19: The Singapore Experience (DOI: 10.1016/j.jvir.2020.03.021)
Perfluorobutane contrast-enhanced ultrasonography: a new standard for ultrasonography-guided thermal ablation of sonographically occult liver tumours? (DOI: 10.11622/smedj.2020061 )
Outcome and Distal Access Patency in Subintimal Arterial Flossing with Antegrade-Retrograde Intervention for Chronic Total Occlusions in Lower Extremity Critical Limb Ischemia (DOI: 10.1016/j.jvir.2019.12.006)
Genomic landscape of lung adenocarcinoma in East Asians ( DOI: 10.1038/s41588-019-0569-6)
Utility of incorporating next-generation sequencing (NGS) in an Asian non-small cell lung cancer (NSCLC) population: Incremental yield of actionable alterations and cost-effectiveness analysis (DOI: 10.1016/j.lungcan.2019.11.022)
Catheter-Directed Computed Tomography Hepatic Angiography for Yttrium-90 Selective Internal Radiotherapy of Hepatocellular Carcinoma Reduces Prophylactic Embolization of Extrahepatic Vessels (DOI: 10.1007/s00270-019-02362-y)
Outcomes of endovascular salvage of clotted arteriovenous access and predictors of patency after thrombectomy (DOI: 10.1016/j.jvs.2019.07.056 )
Single-centre retrospective review of risk factors for local tumour progression and complications in radiofrequency ablation of 555 hepatic lesions (DOI: 10.11622/smedj.2019036 )
Lemmel Syndrome or Biliary Obstruction Due to a Periampullary Duodenal Diverticulum (DOI: 10.1148/radiol.2019162375)
Paclitaxel-coated balloon in the treatment of recurrent dysfunctional arteriovenous access, real-world experience and longitudinal follow up (DOI: 10.1111/nep.13591)
Pseudoaneurysm after vacuum-assisted breast biopsy treated with percutaneous thrombin injection (DOI: 10.1111/tbj.13213)
Clonal MET Amplification as a Determinant of Tyrosine Kinase Inhibitor Resistance in Epidermal Growth Factor Receptor-Mutant Non-Small-Cell Lung Cancer ( DOI: 10.1200/JCO.18.00177 )
Catheter-directed thrombolysis versus percutaneous mechanical thrombectomy in the management of acute limb ischemia: a single center review (DOI: 10.1186/s42155-018-0041-1)
Comparison of alteplase and urokinase for pharmacomechanical thrombolysis of clotted hemodialysis access (DOI: 10.1177/1129729818819735)
Percutaneous Radiologically-Guided Gastrostomy (PRG): Safety, Efficacy and Trends in a Single Institution
A pilot study on adjunctive use of parametric colour-coded digital subtraction angiography in endovascular interventions of haemodialysis access (DOI: 10.1186/s12880-018-0270-8)
Hemodialysis Arteriovenous Fistula and Graft Stenoses: Randomized Trial Comparing Drug-eluting Balloon Angioplasty with Conventional Angioplasty (DOI: 10.1148/radiol.2018170806)
Complications of 90Y Transarterial Radioembolization of Hepatic Tumors: Primer for Interventional Radiology Residents and Fellows RadioGraphics Fundamentals (DOI: 10.1148/rg.2018180062)
Intermediate Outcomes of Image-Guided Radiofrequency Ablation of Renal Tumours
Image-guided Percutaneous Transhepatic Removal of Fish Bone from Liver Abscess (DOI: 10.3941/jrcr.v11i2.2997)
Diagnosis and Management of Complications from Percutaneous Biliary Tract Interventions (DOI: 10.1148/rg.2017160159)
National Cancer Centre Singapore Consensus Guidelines for Hepatocellular Carcinoma (DOI: 10.1159/000367759)
REcanalisation and Balloon-Oriented Puncture for Re-Insertion of Dialysis Catheter in Nonpatent Central Veins (REBORN) (DOI: 10.1007/s00270-016-1383-5)
Current role of selective internal radiation with yttrium-90 in liver tumors (DOI: 10.2217/fon-2016-0035)
Application of a standardised protocol for hepatic venous pressure gradient measurement improves quality of readings and facilitates reduction of variceal bleeding in cirrhotics (DOI: 10.11622/smedj.2016054)
Technical Note: Automatic real-time ultrasound tracking of respiratory signal using selective filtering and dynamic template matching (DOI: 10.1118/1.4924803)
A manifold learning method to detect respiratory signal from liver ultrasound images (DOI: 10.1016/j.compmedimag.2014.11.013)
Single centre experience of transjugular liver biopsy in 152 patients
Randomized clinical trial of cutting balloon angioplasty versus high-pressure balloon angioplasty in hemodialysis arteriovenous fistula stenoses resistant to conventional balloon angioplasty (DOI: 10.1016/j.jvir.2013.10.020)
Post-radioembolization yttrium-90 PET/CT - part 1: diagnostic reporting (DOI: 10.1186/2191-219X-3-56)
Supplementary breast ultrasound screening in Asian women with negative but dense mammograms-a pilot study
Early diagnosis of bowel obstruction and strangulation by computed tomography in emergency department (DOI: 10.5847/wjem.j.issn.1920-8642.2012.03.012)
Stent-assisted percutaneous angioplasty for extra-cranial carotid disease:experience at Singapore General Hospital
Image-guided musculoskeletal biopsy (DOI: 10.1016/j.rcl.2008.04.014)