Assoc Prof Chew Tsong Huey Sophia

A/Prof Sophia Chew is a Senior Consultant with the Department of Anaesthesiology, Singapore General Hospital.

She is also a Visiting Consultant with the Department of Cardiothoracic Anaesthesia, National Heart Centre Singapore. Her interests are in the area of optimizing perioperative and long-term outcomes of patients after cardiac surgery. A/Prof Chew is a key opinion leader from industry based on her expertise in acute kidney injury after cardiac surgery.

• PS21 ExCEL Award 2009
• Wong Hock Boon Society-Singapore Medical Association Outstanding Mentor Award

Current Trial:

• EL DORADO Study (Evaluation of Delivery of Oxygen on Renal Outcomes)

1. ​WEJ Wong, SP Chan, JK Yong, YYS Tham, JRG Lim, MA Sim, Soh CR, Ti LK, STH Chew. Assessment of acute kidney injury risk using a machine-learning guided generalized structural equation model: a cohort study. BMC Nephrol 2021 Feb 22, 22(1): 63 (2021)
2. Y Ke, Chew STH, Ang AS, Ng RRG, Boonkiangwong N, Liu W, Toh AHH, Caleb MG, Ho RCM, Ti LK. Comparison of postoperative cognitive decline in patients undergoing conventional vs miniaturized cardiopulmonary bypass: A randomized, controlled trial. Ann Card Anaesth. 2020 Jul-Sep;23(3):309-314
   MA Sim, LK Ti, S Mujumdar, STH Chew, DJB Penanueva, BM Kumar, SBL Ang. Sustaining the Gains: A 7-year follow-through of a hospital-wide patient safety improvement project on hospital-wide adverse event outcomes and patient safety culture. J of Patient safety. 2020 May 9 [PMID: 32398537]
   Moorthy V, Liu W, Chan SP, Chew STH, Ti LK. Elucidation of the novel role of ethnicity and diabetes in poorer outcomes after cardiac surgery in a multiethnic southeast asian cohort. J Diabetes 2020 Jan;12(1): 58-65
3. Moorthy V, Liu W, Chew STH, Ti LK. Impact of diabetes on outomes of cardiac surgery in a multiethnic Southeast Asian population. Diab Vasc Dis Res. 2019 Nov;16 (6): 549 – 555
4. Saito T, Asai T, Taguchi A, Chew STH, Liu W, Thinn KK, Ti LK. Correlation between failed facemask ventilation, failed ventilation through a supraglottic airway and difficult tracheal intubation in unexpected difficult airways: An observational study. J Clin Anesth 2019 Aug 20; 60: 34-35
5. V Moorthy, MA Sim, Liu W, Chew STH, Ti LK. Risk factors and impact of postoperative hyperglycemia in nondiabetic patients after cardiac surgery. Medicine June 2019 - Vol 98 (23): e15911
6. Chew STH, Ti LK. Research in Anaesthesia  - The PEGASUS Journey. The Asia-Pacific Scholar Medical and Health Professions Education. May 2019, 4(2), 60 – 62
7. Saw KME, Ng RGR, Chan SP, Ang YH, Ti LK, Chew STH. Association of genetic polymorphisms with acute kidney injury after cardiac surgery in a Southeast Asian population. PLOS One 2019 Apr 11;14(4):e0213997
8. Chew STH, Hwang NC. Acute Kidney Injuy after cardiac surgery: a narrative review of the literature. J Cardiothorac Vasc Anesth 2019 Apr;33(4):1122-1138
9. Lu A, Chew STH. Successful use of extracorporeal cardiopulmonary membrane oxygenation in acute severe aortic regurgitation with cardiovascular collapse. Proceedings in Singapore Healthcare 2019 Mar Vol 28(1): 65-67
10. V Moorthy, MA Sim, Liu W, Ti LK, Chew STH. Association between ethnicity and postoperative hyperglycemia in a South East Asian Population undergoing cardiac surgery. Journal of Cardiothoracic and Vascular Anesthesia. 2019 Feb; 33(2): 388-393
11. Sim MA, Liu W, Chew STH, Ti LK. Wider perioperative glycemic fluctuations increase risk of postoperative atrial fibrillation and ICU length of stay. PLoS ONE 2018 Jun 13(6): e0198533
12. Chew STH, Ng RRG, Liu W, Chow KY, Ti LK. Acute kidney injury increases the risk of end-stage renal disease after cardiac surgery in an Asian population: a prospective cohort study. BMC Nephrology. 2017 Feb 13;18(1) :60.