Follow the directions on the medicine label and administer the medicine exactly as directed. Do not administer more or less than what is prescribed by your doctor. The dose for each patient is individually determined by the doctor.
Take the missed dose as soon as you remember. However, if you omissed the dose for more than half the time interval (e.g. more than 4 hours for an 8-hourly dosing), skip the missed dose and administer the medicine at the usual time. Inform your doctor if you missed 3 days or more of the regular prescribed dose. DO NOT take two doses at the same time to make up for a missed one.
In cases you or someone else may have taken an overdose of Methadone tablets, get an emergency help and call 995 immediately.
Signs and symptoms of overdose include cold clammy (pale) skin, confusion, seizures, severe dizziness (low blood pressure), severe drowsiness, severe nervousness or restlessness, slow or troubled breathing and severe weakness. Overdose can result in sudden death.