Heritable Retinoblastoma

What are the features of retinoblastoma?

If parents notice one or more of the following features suggestive of retinoblastoma, they should consult an eye specialist as soon as possible.

• Leukocoria or a white pupil, especially with flash photography
  
• Vision problems
  
• Red or irritated eyes
• Strabismus or misaligned eyes (one eye turns in/out/up/down when the child is looking straight ahead)
  
  

What are the tumour and cancer risks associated with heritable retinoblastoma?

Heritable retinoblastoma is associated with a faulty RB1 gene present in every cell of the body, which increases the lifetime risk of developing other tumours or cancers.

Note: The conditions associated with a faulty RB1 gene and their risk estimates may change as more information is available.