Prostate Cancer Imaging Program

As a clinical radiologist who subspecializes in genitourinary radiology, Dr Law Yan Mee's clinical interests include benign and malignant male and female genitourinary diseases, structural and functional pelvic floor disorders, kidney cancer and prostate cancer.  Dr Law believes in the critical role of radiologists in clinical support and endeavors to support her clinical colleagues in the areas of clinical care and research.

Dr Law's research interests include the use of Magnetic Resonance Imaging (MRI) in early detection of prostate cancer, risk stratification in patients at risk of developing prostate cancer, focal therapy in treatment of localized prostate cancer, endometriosis and gynecology cancers. Together with the urologists from Department of Urology (SGH), they pioneered the use of MRI in early detection of prostate cancer in at risk patients through MRI-ultrasound fusion targeted robotic biopsy. Dr Law has also collaborated with Clinical Assistant Professor Tay Kae Jack from the Department of Urology (SGH) and a co-investigator in a NMRC Clinician Scientist Individual Research Grant in focal therapy of prostate cancer.

Contact

Please contact Dr Law Yan Mee at law.yan.mee@singhealth.com.sg for more information.

Publications:

1. Lee AY, Yang XY, Lee HJ, Law YM, Hong HH, Lau WK, Lee LS, Ho HS, Tay KJ, Cheng CW, Yuen JS, Chen K. Multiparametric MRI-ultrasonography software fusion prostate biopsy: initial results using a stereotactic robotic-assisted transperineal prostate biopsy platform comparing systematic vs targeted biopsy: Stereotactic robotic-assisted transperineal prostate biopsy. BJU Int. 2020;126(5):568-576. doi:10.1111/bju.15118

2. Yang X, Lee AY, Law YM, Sim ASP, Tay KJ, Lau WKO, Ho HSS, Yuen JSP, Chen K. Stereotactic robot-assisted transperineal prostate biopsy under local anaesthesia and sedation: moving robotic biopsy from operating theatre to clinic. J Robot Surg. 2020;14(5):767-772. doi:10.1007/s11701-020-01052-z

3. Aslim EJ, Law YXT, Fook-Chong SMC, Ho HSS, Yuen JSP, Lau WKO, Lee LS, Cheng CWS, Ngo NT, Law YM, Tay KJ. Defining prostate cancer size and treatment margin for focal therapy: does intralesional heterogeneity impact the performance of multiparametric MRI? BJU Int. 2021 Feb doi: 10.1111/bju.15355. Epub ahead of print.

4. Greer MD, Lay N, Shih JH, Barrett T, Bittencourt LK, Borofsky S, Kabakus I, Law YM, Marko J, Shebel H, Mertan FV, Merino MJ, Wood BJ, Pinto PA, Summers RM, Choyke PL, Turkbey B. Computer-aided diagnosis prior to conventional interpretation of prostate mpMRI: an international multi-reader study. Eur Radiol. 2018 Oct;28(10):4407-4417. doi: 10.1007/s00330-018-5374-6. Epub 2018 Apr 12.

5. Chen K, Tay KJ, Law YM, Aydin H, Ho H, Cheng C, Yuen JSP. Outcomes of combination MRI-targeted and transperineal template biopsy in restaging low-risk prostate cancer for active surveillance. Asian J Urol. 2018 Jul;5(3):184-193. doi: 10.1016/j.ajur.2017.07.001. Epub 2017 Jul 12.

6. Aslim EJ, Law YM, Tan PH, Allen JC Jr, Cheng LT, Chidambaram VA, Khor LY, Tan BY, Eu EW, Cheng CWS, Yuen JSP, Ho HSS, Lee LS. Multiparametric MRI reporting using Prostate Imaging Reporting and Data System version 2.0 (PI-RADSv2) retains clinical efficacy in a predominantly post-biopsy patient population. Asian J Urol. 2019 Jul;6(3):256-263. doi: 10.1016/j.ajur.2018.05.008. Epub 2018 Jun 1.

7. Sackett J, Shih JH, Reese SE, Brender JR, Harmon SA, Barrett T, Coskun M, Madariaga M, Marko J, Law YM, Turkbey EB, Mehralivand S, Sanford T, Lay N, Pinto PA, Wood BJ, Choyke PL, Turkbey B. Quality of Prostate MRI: Is the PI-RADS Standard Sufficient? Acad Radiol. 2021 Feb;28(2):199-207. doi: 10.1016/j.acra.2020.01.031. Epub 2020 Mar 4.