Patients presenting with acute ischemic stroke secondary to an intracranial large vessel occlusion can benefit from endovascular thrombectomy within 24h of symptom onset. In patients presenting within 4.5hrs, the non-inferiority of direct to mechanical thrombectomy versus thrombolysis with mechanical thrombectomy is unknown and SGH is one of the participating centres for the DIRECT-SAFE multicentre prospective randomized trial.
There is a direct correlation between better clinical outcomes with faster time from stroke onset to recanalisation. We are actively involved in research and quality improvement processes to develop new systems of care to reduce the time taken for our patients to undergo appropriate imaging evaluation and treatment (thrombolysis and mechanical thrombectomy).
The Singapore General Hospital Neurointerventional Radiology (NIR) team led by A/Prof Winston Lim, specializes in the diagnosis and treatment of vascular diseases affecting the brain and neck. The NIR team works closely with other clinical specialties such as Neurology, Neurosurgery and ENT; to deliver the best in multidisciplinary patient care.
Part of the NIR team's research interest is the use of high-resolution magnetic resonance imaging (MRI) to study various intracranial vascular diseases. The team is now able to use high-resolution MRI, or commonly known as Vessel Wall Imaging (VWI), to visualize the wall of small intracranial arteries rather than rely on conventional imaging techniques which only assess calibre of the vessel lumen. This translates into increased accuracy of diagnosing different intracranial vascular diseases and allows clinicians to tailor their treatment for patients.
For further information, please contact A/Prof Winston Lim, Dr Chia Ghim Song and Dr David Wen
A/Prof Winston Lim Eng Hoe - firstname.lastname@example.org
Dr Chia Ghim Song - email@example.com
Dr David Wen - firstname.lastname@example.org