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The Biomechanics Laboratory (BML) at Singapore General Hospital stands as Singapore's only comprehensive hospital-based facility capable of conducting in-vitro tissue research. As a collaborative workspace for multi-disciplinary research and innovation, we serve as a vital bridge connecting researchers, clinicians, students, and industrial partners from various institutions, both locally and internationally. Our extensive network facilitates the dynamic exchange of expertise, resources, and innovative ideas.
Our laboratory comprises two specialised units: Cell and Tissue Bioengineering (CTBioE) and Robot Enhanced Biomechanics and Engineering Laboratory (REBEL).
Our research strengths and capabilities are in the following categories:

Academia, Level 1, 20 College Road
+65 6576 7962
Academia, Level 1, 20 College Road
+65 6576 7446
BML's current flagship research focuses on investigating osteoarthritis in the small joint such as wrist and fingers, with particular emphasis on aging-related conditions. This comprehensive studies, supported by multiple SingHealth Academic Medicine (AM) Grants, represents a collaborative effort between our team and clinicians from the Department of Hand and Reconstructive Microsurgery (HRM) and Occupational Therapy (OT).
REBEL serves as our dedicated research facility for orthopaedic biomechanics research, providing domain-specific expertise in large joints biomechanics using cadaver specimens and specialised equipment. Our facilities are strategically located across Academia:
Our advanced equipment includes:
REBEL's research portfolio spans several critical areas in biomechanical engineering, including comprehensive studies of large joints in both lower and upper extremities, examining these structures in intact, damaged, and surgically repaired states.
1. Joint Biomechanics Studies
We perform detailed kinematic and kinetic investigations across different joints, developing deeper insights into join diseases and movement patterns. These studies provide crucial information for understanding joint function and pathology.
2. Implant Design and Analysis
Using advanced computer-aided techniques, we design novel implants and analyze their mechanical interactions within joints of interest. This work contributes to the development of more effective and durable implants for various orthopaedic applications.

3. Robotic Knee Tester Development
We're creating an innovative system that integrates robotic testing with motion capture technology. This setup allows for precise control and measurement of knee joint mechanics while simultaneously capturing real-time motion data. The integration of motion capture with robotic testing bridges the gap between cadaveric studies and real-world functional biomechanics, enabling us to validate robotic simulations against actual human movement data.
4. Personalized Tele-rehabilitation
We're working on customizing rehabilitation protocols using our research data. This approach aims to detect potential complications such as abnormal loading or improper joint movement, allowing for early intervention to prevent secondary injuries. By personalizing rehabilitation, we hope to improve patient outcomes and recovery times.
Through these diverse projects, REBEL aims to advance our understanding of joint biomechanics and improve patient outcomes in orthopedic care. Our multifaceted approach combines cutting-edge technology with clinical expertise to address pressing challenges in biomechanical engineering and orthopedic medicine.
We aim to establish a robust ecosystem for computational simulation in biomedical engineering, advancing orthopaedics biomechanics research at SGH. Our vision is to build a credible global reputation as an outstanding academic clinical programme centre that can influence the future of healthcare through cutting-edge research.
Our goal is to enhance patient outcomes by ensuring a data-driven, patient-specific approach to postoperative care, ultimately leading to improved mobility, faster recovery times, and better long-term joint health. We strive to benefit patients through well-predicted, precise, and optimised surgical outcomes.
Our laboratory brings exceptional strength in computational simulation, fostering valuable cross-collaborative opportunities with Principal Investigators from Orthopaedic, Cardiovascular, and Ophthalmology departments. We offer comprehensive support including:
We are always ready to engage with interested parties that require our expertise. Our services extend to grant writing and submission, project management and execution, data analysis, results interpretation, and manuscript writing when required.
Ready to be part of our transformative journey?
Innovation waits for no one. Get in touch with us.
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