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Clin Assoc Prof Wong Gee Chuan

Clin Assoc Prof Wong Gee Chuan

MBBS, MMed(Int Med), FRCP(Edin), FAMS

Senior Consultant

Singapore General Hospital

Specialty: Haematology

Sub-specialties: Acute Leukemia, Myeloid Neoplasms

Conditions Treated by this Doctor:
Acute Lymphocytic Leukemia (ALL), Acute Myelogenous Leukemia (AML), Aplastic Anaemia, Chronic lymphocytic leukemia, Chronic lymphocytic leukemia, Chronic Myeloid Leukemia (CML), Deep Vein Thrombosis, Deep Vein Thrombosis, Deep Vein Thrombosis, Deep Vein Thrombosis, essential thrombocythemia, Multiple Myeloma, Myelodysplastic Syndromes, Myelodysplastic Syndromes, Myelofibrosis, Polycythemia Vera, Pulmonary Embolism, Thalassaemia, Thalassaemia.

Clinical Appointments

  • Senior Consultant SingHealth Duke-NUS Blood Cancer Centre
  • Senior Consultant Haematology Singapore General HospitalSingapore General Hospital

Academic Appointments

  • Adjunct Associate Professor, Yong Loo Lin School of Medicine, National University of Singapore
  • Adjunct Associate Professor, Duke-NUS Medical School

Profile

Dr Wong’s interest is in malignant haematology. Her special interest is in acute leukemias. Trained in MD Anderson Cancer Center, Houston, Texas, Dr Wong spearheaded the setup of the Leukemia Registry and Myeloproliferative Disorders Registry in the Department of Hematology, Singapore General Hospital and developed leukemia protocols, antibiotics and antifungal guidelines for immunocompromised hosts.

Besides authoring patient guidebooks on leukemias, lymphoma and febrile neutropenia, she has also published on malignant haematology, myeloproliferative neoplasm, febrile neutropenia and invasive fungal Infections. She is also a principal investigator in multiple trials in these areas.

Besides contributing actively in advisory boards, Dr Wong is also a reviewer for medical and hematology journals and has also been appointed as examiner in multiple medical examinations. She has won multiple academic and scientific awards at national and international scientific meetings and has also been awarded multiple Excellent Service Awards and Star Awards.

Dr Wong received specialist accreditation in Palliative Medicine in 2010 and has an interest in Palliative Medicine in hematological malignancies.

Education

  • ​FAMS (Hematology) 2000
  • Specialist Accreditation in Palliative Medicine 2010
  • FRCP (Edinburgh) 2005
  • M. Med (Internal Medicine) 1995
  • MBBS (Singapore) 1990

Professional Appointments and Committee Memberships

  • Lead, Acute Leukemia Service, Department of Hematology, Singapore General Hospital
  • Chairman, Singapore Leukemia Workgroup
  • Adjunct Associate Professor, Yong Loo Lin School of Medicine, National University of Singapore
  • Clinical Associate Professor, Duke-NUS Medical School
  • Member, Asian Myeloid Working Group

Awards

  • Dean’s Award for Teaching Excellence CE (AY13/14)
  • Excellence Service Awards 2004, 2007-2011
  • SingHealth Quality Service Award 2015
  • Singapore Health Quality Service Award 2016
  • Dean’s Award for Teaching Excellence CE (AY13/14)
  • Excellence Service Awards 2004, 2007-2011
  • SingHealth Quality Service Award 2015
  • Singapore Health Quality Service Award 2016

Research Interests

Publications

  • Zhou PY, Lim TP, Tang SLS, Lim J Le, Liew Y, Chua NG, et al. Therapeutic drug monitoring is necessary for patients receiving posaconazole tablet. Vol. 82, The Journal of infection. England; 2021. p. e18–21.
  • Zhou PY, Lim TP, Tang SLS, Liew Y, Chua SGN, Lim LLC, et al. The utility of voriconazole therapeutic drug monitoring in a multi-racial cohort in Southeast Asia. J Glob Antimicrob Resist. 2020 Jun;21:427–33.
  • Lao Z-T, Ding L-W, An O, Hattori N, Sun Q-Y, Tan K-T, et al. Mutational and transcriptomic profiling of acute leukemia of ambiguous lineage reveals obscure but clinically important lineage bias. Vol. 104, Haematologica. 2019. p. e200–3.
  • Chen C, Heng EYH, Lim AST, Lau LC, Lim TH, Wong GC, et al. Chromosomal microarray analysis is superior in identifying cryptic aberrations in patients with acute lymphoblastic leukemia at diagnosis/relapse as a single assay. Int J Lab Hematol. 2019 Aug;41(4):561–71.
  • Zhou PY, Lim TP, Tang SLS, Lee HLW, Tan TT, Tan BH, et al. Subtherapeutic posaconazole troughs despite high-dose posaconazole tablets in a patient with terminal ileum resection. Vol. 78, The Journal of infection. England; 2019. p. 409–21.
  • Ong SY, Li S-T, Wong GC, Ho AYL, Nagarajan C, Ngeow J. Delayed diagnosis of Shwachman diamond syndrome with short telomeres and a review of cases in Asia. Vol. 9, Leukemia research reports. 2018. p. 54–7.
  • Tan BH, Guzman MRT De, Donato LKS, Kalimuddin S, Lee WHL, Tan AL, et al. Impact of an alternating first-line antibiotics strategy in febrile neutropenia. PLoS One. 2018;13(11):e0208039.
  • Keng BM, Wong GC. Osteonecrosis in Adolescents and Young Adults with Acute Lymphoblastic Leukaemia on Hong Kong-Singapore Acute Lymphocytic Leukaemia 97 Protocol. Vol. 46, Annals of the Academy of Medicine, Singapore. Singapore; 2017. p. 293–7.
  • Keng M-HB, Keng H-LC, Tan B-H, Wong G-C. High risk of invasive fungal infections in adult acute lymphoblastic leukemia  patients receiving induction and salvage chemotherapy. Vol. 58, Leukemia & lymphoma. United States; 2017. p. 2017–8.
  • Lao Z, Yiu R, Wong GC, Ho A. Treatment of elderly patients with acute myeloid leukemia with azacitidine results in fewer hospitalization days and infective complications but similar survival compared with intensive chemotherapy. Asia Pac J Clin Oncol. 2015 Mar;11(1):54–61.
  • Kam G, Yiu R, Loh Y, Ang AL, Yueh LL, Goh YT, et al. Impact of pegylated filgrastim in comparison to filgrastim for patients with acute myeloid leukaemia (AML) on high-dose cytarabine (HIDAC) consolidation chemotherapy. Support care cancer Off J Multinatl Assoc Support Care Cancer. 2015 Mar;23(3):643–9.
  • Wong GC. Hyperleukocytosis in acute myeloid leukemia patients is associated with high 30-day mortality which is not improved with leukapheresis. Vol. 94, Annals of hematology. Germany; 2015. p. 2067–8.
  • Wong G-C, Abdul Halim NA, Tan B-H. Antifungal Prophylaxis With Posaconazole Is Effective in Preventing Invasive Fungal Infections in Acute Myeloid Leukemia Patients During Induction and Salvage Chemotherapy. Vol. 61, Clinical infectious diseases: an official publication of the Infectious Diseases Society of America. United States; 2015. p. 1351–2.
  • Tan BH, Png ME, Yeo CP, Wong GC. Procalcitonin in febrile neutropenia--timing is important. Vol. 22, Supportive care in cancer: official journal of the Multinational Association of  Supportive Care in Cancer. Germany; 2014. p. 583–4.
  • Tan DEK, Foo JN, Bei J-X, Chang J, Peng R, Zheng X, et al. Genome-wide association study of B cell non-Hodgkin lymphoma identifies 3q27 as a susceptibility locus in the Chinese population. Nat Genet. 2013 Jul;45(7):804–7.
  • Liew Y-X, Tan T-T, Lee W, Ng J-L, Chia D-Q, Wong G-C, et al. Risk factors for extreme-drug resistant Pseudomonas aeruginosa infections in patients with hematologic malignancies. Am J Infect Control. 2013 Feb;41(2):140–4.
  • Wong K-Y, Tai B-C, Chia S-E, Kuperan P, Lee K-M, Lim S-T, et al. Sun exposure and risk of lymphoid neoplasms in Singapore. Cancer Causes Control. 2012 Jul;23(7):1055–64.
  • Tan BH, Low JGH, Chlebicka NL, Kurup A, Cheah FK, Lin RTP, et al. Galactomannan-guided preemptive vs. empirical antifungals in the persistently febrile neutropenic patient: a prospective randomized study. Int J Infect Dis  IJID  Off Publ  Int Soc Infect Dis. 2011 May;15(5):e350-6.
  • Yiu CR, Lee LH, Kumar PM, Wong GC. A patient with extramedullary acute myeloid leukaemia involving the brachial plexus:  Case report and review of the literature. Turkish J Haematol  Off J Turkish Soc Haematol. 2008 Jun;25(2):98–100.
  • Wong GC, Tan BH. Use of antibiotics in a haematology ward--an audit. Ann Acad Med Singapore. 2008 Jan;37(1):21–6.
  • Wong GC, Lee LH. Acute biphenotypic leukemia arising in a patient with essential thrombocythemia. Am J Hematol. 2006 Aug;81(8):624–6.   

Research Trials