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Prof Tay Sun Kuie

Tay Sun Kuie

Prof Tay Sun Kuie

​MBBS, FRCOG (UK), MD (Lond), FAMS, MAppLaw

Senior Consultant

Specialty: Obstetrics & Gynaecology

Sub-specialties: Gynaecological Tumours and Cancers, Endometriosis

Clinical Appointments

  • Senior Consultant Obstetrics & Gynaecology Singapore General HospitalSingapore General Hospital

Academic Appointments

  • Duke-NUS Medical School
  • NUS Yong Loo Lin School of Medicine


​Professor Tay graduated from the University College London, UK with a basic degree in MBBS and a higher degree in MD with a thesis entitled “Local Cervical Immune Reactions to Human Papillomavirus Infection and Its Associated Neoplasia”. He took specialist training in obstetrics & gynaecology in London and received subspecialty training in colposcopy and laser treatment of pre-invasive disease of the cervix while working with Professor Albert Singer PhD, Dphil (Oxon), FRCOG in London from 1982 to 1987. He also took a fellowship of the Ministry of Health, Singapore for a special interest in immunotherapy of gynaecological cancer at the MD Anderson Medical Centre and Institute of Tumours, Houston, Texas, USA in 1993.  Professor Tay was admitted to the fellowship of the Academy of Medicine, Singapore (FAMS) in 1989 and the Royal College of Obstetricians and Gynaecologists London (FRCOG) in 1998.

Prof Tay provides a full range of out-patient services and surgeries in obstetrics and gynaecology and carries subspecialty clinical privileges in Singapore General Hospital for colposcopy, women’s cancer surgery, minimally invasive surgery, therapeutic hysteroscopy and surgery for female urinary stress incontinence. He also has a special interest in treatment of endometriosis.

Prof Tay is a faculty member in academic clinical program for training of residents in obstetrics and gynaecology. He also maintains a long-term research interest in human papillomavirus infection and women’s cancer. He has written a book on “Cervical cancer: Its Causes and Prevention” and has contributed chapters to many text books in gynaecology. He has also published more than 100 research papers in peer reviewed medical and scientific journals.


  • MBBS
  • FRCOG (UK)
  • MD (Lond)
  • FAMS
  • MAppLaw

Professional Appointments and Committee Memberships

  • Senior Consultant Obstetrician & Gynaecologist, SGH 
  • Chief, Section of Gynaecologic Oncology, SGH 
  • Visiting Senior Consultant, National Cancer Centre Singapore 
  • Gynaecologic Oncologist, SGH Specialist Practice, Gleneagles Hospital 
  • Member, International Society of Gynaecologic Cancers 
  • Past President, Society for Colposcopy and Cervical Pathology Singapore


  • Hamilton & Bailey Prize in Surgery 1987 
  • National Science Award 1996
  • 16th Benjamin Sheares Memorial Lectureship 1997
  • Excellent Publication Award 1999
  • Review with Distinction Award, Singapore Medical Journal, 2005. 2006, 2008

Research Interests


Research Trials

  • Details of publications @ Google Scholar
  • Singer A, Walker PG, Tay SK, Dyson JL (1984) Impact of the introduction of colposcopy in a district general hospital. Br Med J; 289: 1049-51
  • Jenkins D, Tay SK, Dyson JL (1986).Koilocyte frequency and prevalence of cervical human papillomavirus infection. Lancet; 1 :557-58
  • Jenkins D, Tay SK, McCance DJ, Campion MJ, Clarkson PK, Singer A (1986). Histological and immunocytochemical study of HPV 6 and 16 infection associated with CIN. J Clin Pathol; 39 (11) : 1177- 80
  • Jenkins D and Tay SK (1987).Management of mildly abnormal cervical smears.Lancet; 1: 748-59.
  • Jenkins D, Tay SK, Maddox P (1987).Routine papillomavirus antigen staining of cervical punch biopsy specimen.J Clin Pathol; 40: 1212-16.
  • Singer A, Tay SK, Griffin JFA, Wickens D, Dormandy TL (1987).Diagnosis of cervical neoplasia by the estimation of octadeca-9, 11-dienoic acid. Lancet; 1 : 537-39
  • Tay SK, Jenkins D, Maddox P, Campion MJ, Singer A (1987). Subpopulation of Langerhan’s cells in cervical neoplasia. Br J Obst Gynae; 94 (1): 10-15.
  • Tay SK, Jenkins D, Maddo P, Hogg N, Singer A (1987).Tissue macrophage response in cervical intraepithelial neoplasia and human papillomavirus infection. Br J Obst Gynae; 94: 1094-97
  • Tay SK, Jenkins D, Maddox P, Singer A (1987). Lymphocyte phenotypes in cervical intraepithelial neoplasia and human papillomavirus infection. Br J Obst Gynae; 94 (1): 16-21
  • Tay SK, Jenkins D, Singer A (1987)        Natural killer cells in cervical intraepithelial neoplasia and human papillomavirus infection. Br J Obst Gynae; 94: 901-906
  • Wickens DG, Davies MJ, Fairbank J, Tay SK, Slater TF, Dormandy TL (1990) Studies on cervical intraepithelial neoplasia: the level of octadeca-9, 11-dienoic acid and measurement of free radical content by electron spin resonance spectroscopy. Am J Obst Gynae; 162 : 854-58
  • Ho L, Tay SK, Chan SY, Bernard HU (1993). Sequence variants of human papillomavirus type 16 from couples suggest sexual transmission with low infectivity and polyclonality in genital neoplasia. J Infect Dis; 168: 803-809
  • Tay SK (1995) Endometrial surveillance in postmenopausal breast cancer patients treated with Tamoxifen. JAMA; 11 (6): 8-9
  • Chia SE, Ong CN, Chua LH, Ho LM, Tay SK (2000) omparison of zinc concentrations in blood and seminal plasma and the various sperm parameters between fertile and infertile men. Journal of Andrology, 2000; 21(1): 53-7
  • Chia SE, Lim ST, Ho LM, Tay SK (2001) Monthly variation in human semen quality in male partners of infertile women in the tropics.Human Reprod. 2001 Feb; 16(2): 277-81
  • Hu WP, Tay SK (2002) Identification of differential gene expression in human endometriosis by subtractive hybridization and gene expression profiling with real-time PCR. Fertil Steril. 2002 Feb; 77, Suppl 1:S17
  • Lim AST, Lim TH, Kee SK,Chieng R,Tay SK (2003) Sperm segregation patterns by fluorescence in situ hybridization studies of a 46,XY,t(2;6) heterozygote giving rise to a rare triploid product of conception with a 69 Y,t(2;6)(p12;q24)der(6)t(2;6)(p12;q24)pat karyotype. Am J Med Genet. 2003 Mar 1;117A(2):172-6.
  • SK Tay, KJ Tay (2004) Passive Cigarette Smoking is a Risk Factor in Cervical Neoplasia. Gynaecologic Oncology 93 (2004) 116 – 220
  • Hu WP, Tay SK, Zhao Y (2006) Endometriosis-specific genes identified by real-time reverse transcription- polymerase chain reaction expression profiling of endometriosis versus autologous uterine endometrium.J Clin Endocrinol Metab. 91(1):228-38.
  • Leong CT, Ong CK, Tay SK, Huynh H (2007) Silencing expression of UO-44 (CUZD1) using small interfering RNA sensitizes human ovarian cancer cells to cisplatin in vitro. Oncogene 26(6):870-80. 
  • Tay SK, Ngan HY, Chu TY, Cheung AN, Tay EH (2008) Epidemiology of human papillomavirus infection and cervical cancer and future perspectives in Hong Kong, Singapore and Taiwan. Vaccine. 2008 Aug 19;26 Suppl 12:M60-70