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Prof Tay Boon Keng

Prof Tay Boon Keng

​MBBS, FRCS (Edin), FRCS (Edin)(Ortho), FAMS, FACS, Clinical Professor

Emeritus Consultant

Singapore General Hospital

Specialty: Orthopaedic Surgery

Clinical Interest: Adult Reconstruction Service

Conditions Treated by this Doctor:
Anterior Cruciate Ligament (ACL) Reconstruction, Anterior Cruciate Ligament Reconstruction, Knee Arthroscopy, Knee Injuries, Total Knee Replacement.

Clinical Appointments

  • Emeritus Consultant Orthopaedic Surgery Singapore General HospitalSingapore General Hospital


​Prof Tay’s special area of professional interest is in Knee Surgery. His expertise is sought both in local and overseas hospitals and medical centres and has held numerous professional and academic appointments both in Singapore and abroad.

His scholarly interests have extended to attending the Harvard Business School Executive Education Program – Governing for Non-Profit Excellence: Critical Issues for Board Leadership in 1999.  He also attended the Harvard Business School Advanced Management Program in 2000 and the Harvard Macy Institute Program for Leaders in Medical Education this year.

As the immediate past Chairman, Medical Board, International, SingHealth, Prof Tay frequently leads a team of doctors, nurses and allied health specialists for medical and academic exchanges with overseas medical institutes with the aim of identifying and nurturing both local and overseas staff to excel in their field of expertise as well as to establish good working relationships with these institutes.


  • University of Singapore    - M.B.B.S. ( 1973 )
  • Royal College of Surgeons, Edinburgh   - FRCS Edin ( 1977 )
  • Royal College of Surgeons, Edinburgh   - FRCS Edin (Ortho) ( 1981 )
  • Academy of Medicine, Singapore   - FAMS ( 1981 )
  • American College of Surgeons     - FACS ( 1995 )

Professional Appointments and Committee Memberships


Research Interests


Publications – ( focused  on  tissue  engineering )
  1. Autologous Marrow Injection in the Treatment of delayed and non-union in long bones. Singapore Medical Journal, October 1993, Vol. 34, pp. 412 – 417.
  2. Anterior Cruciate Ligament Reconstruction Using Patellar Tendon Autografts – A Review Result, Singapore Medical Journal 1997, Vol 38(12)
  3. Patellar Allografts in Anterior Cervical Fusion: A Clinical and Radiological Study – Journal of Spine Manuscript No. 00165
  4. A Comparative Study Between Autogenous Tibial Periosteal Transplants and Mosaicplasty for Full Thickness Articular Cartilage Defects in the Knee Joints – The Journal of the Asean Orthopaedic Association Vol.13 No.1,  July 2000
  5. Autogenous Osteochondral Morselised Grafts for Full Thickness, Osteochondral Defects in the Knee Joints of Pigs – Arjandas Mahadev, Deepak P Mahara, P Chang, AK Mitra, BK Tay, CS Sim Singapore Med J 2001  Vol 42(9) :  410-416.
  6. Complications of total knee arthroplasty – Alan Cheung, Seo Kiat Goh, Andrew Tang, Tay Boon Keng. Current Orthopaedics,  Volume 22,  Issue 4,  August 2008  ISSN 0268-0890

Research Trials

Clinical  Trials  and  Funding
  1. Principal Investigator  –  “An Active Comparator-controlled, parallel-group, 6-week, double-blind study.  Conducted under in-house blinding conditions to assess the safety and efficacy of MK-0966 vs. Naproxen in patients with Osteoarthritis of the knee or hip”.  Funding obtained:  $52,150.
  2. Principal Investigator – “A multi-centre, open-label, randmoised, crossover, preference study of Oral Alendronate 70 mg once weekly and Alendronate 10mg once daily in post-menopausal women with Osteoporosis”.  Funding  S$7,800.
  3. Principal Investigator –  “An international, multi-centre, stratified, randomised, double-blind, double-dummy, parallel-group, 52-week Gastrointestinal Clinical Safety Study to demonstrate that COX 189 (400 mg o.d.) reduces the risk to develop complicated ulcers as compared to Naproxen (500 mg b.l.d) in Rheumatoid Arthritis and Osteoarthritis patients”.  Funding obtained:  S$38,000.
  4. Principal Investigator   –  “A Randomised, double-blind, multi-centre study to evaluate the tolerability and effectiveness of Etoricoxib 90 mg q.d. vs. Diclofenac Sodium 50 mg tid in patients with Osteoarthritis”.  Funding obtained:  S$31,131.75 (EC #128/2002).
  5. Principal Investigator   –   “Compliance and Health Outcomes Osteoporosis Study of Evista in Asia (CHOOSE-A):  An Asian Observational Study to Evaluate Compliance, Health Outcomes and Treatment Satisfaction Associated with Evista vs. Bisphosphonates in post-menopausal women”.  Funding obtained:  S$30,900. Abstract : “Comparison of raloxifene and bisphosphonates on adherence, health outcomes and treatment satisfaction in postmenopausal Asian women” – A W Kung, E G Pasion, D K Sivananthan, S H Chen, B K Tay, G A Shah, F Tam, C M Markey, D Thiebaud.
  6. Principal Investigator  –   “Comparison of Teriparatide and Calcitonin in the treatment of post-menopausal women with Osteoporosis”.  Funding obtained:  S$34, 581.
  7. Principal Investigator   –   “Clinical Protocol for a multi-centre, double-blind, double-dummy, randomised study of the Analgesic Efficacy and Safety of Valdecoxib compared to Doclofenac Sodium in patients undergoing Knee Arthroscopy procedure for Anterior Cruciate Ligament Reconstruction”.  Funding obtained:  S$20,745.