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Clin Asst Prof Rajneesh Kumar

Clin Asst Prof Rajneesh Kumar

​MBBS (India), MD (Med)(India), MRCP (UK)

Senior Consultant

Specialty: Gastroenterology & Hepatology

Clinical Interest: Hepatology, Viral Hepatitis, Liver Failure, Liver Transplant, Diagnostic and Therapeutic Endoscopy

Conditions Treated by this Doctor:
Alcoholic Liver Disease, Autoimmune Hepatitis, Cirrhosis, Colon Cancer Screening, Colonic Polyps, Fatty Liver, Functional Dyspepsia, Gastroesophageal Reflux (GER) and Gastroesophageal Reflux Disease (GERD), Hepatitis B, Hepatitis C, Irritable Bowel Syndrome (IBS), Liver Cancer, Liver Cancer (Hepatocellular Carcinoma), Liver Failure, Liver Transplant, Metabolic Liver Disease, Non-alcoholic Fatty Liver Disease (NAFLD), Non-alcoholic Steatohepatitis (NASH), Reflux/Gastro Oesophageal Reflux, Viral Hepatitis.

Clinical Appointments

  • Senior Consultant Gastroenterology & Hepatology Singapore General HospitalSingapore General Hospital

Academic Appointments

  • Clinical Assistant Professor, Duke-NUS Graduate Medical School
  • Clinical Senior Lecturer, Yong Loo Lin School of Medicine
  • Clinical Teacher, Lee Kong Chian School of Medicine


​Dr Rajneesh Kumar completed his MBBS at SN Medical College, Agra and subsequently his MD ( Medicine) from SMS Medical College Jaipur , India in 2001. He has been working in Singapore General Hospital since 2004.

He obtained his MRCP (UK) in 2008 and completed his specialist training in 2012.
Dr Rajneesh's key research interest are in viral hepatitis and acute chronic liver failure, he has also published numerous articles in this field.


  • ​MBBS – SN Medical College, Agra India
  • MD ( Medicine ) SMS Medical College, Jaipur, India
  • MRCP (UK)  2008
  • Advanced Specialist Training, Singapore 2012

Professional Appointments and Committee Memberships

  • Member , Gastroenterology society of Singapore (GESS)
  • Adjunct Instructor, Singhealth Duke-NUS Academia clinical program
  • Faculty, Residency program
  • Senior Clinical lecturer in NUS Yong Loo Lin School of Medicine
  • Chairman, Treatment assistance program committee, National foundation of Digestive Disease


  • ​HMDP award in Therapeutic advances in Viral hepatitis, INSERM , Lyon, France 2014

Research Interests


  • Coomb’s Negative Autoimmune Hemolytic Anemia with Thrombocytopenia (Evan’s Syndrome) –JAPI Feb 2002; Maheshwari VD, Kumar R, Singh S
  • Identification of Serum Monocyte Chemoattractant Protein-1 and Prolactin as Potential Tumor Markers in Hepatocellular Carcinoma.Wang WW, Ang SF, Kumar R, Heah C, Utama A, Tania NP, Li H, Tan SH, Poo D, Choo SP, Chow WC, Tan CK, Toh HC. PLOS ONE 2013 Jul 18;8(7):e68904.
  • A case report of Shewanella algae cholangitis and bacteremia after snake grass ingestion. Is snake grass a potential source for Shewanella?  Case Study Case Report Case Study Case Rep. 2014; 4(1): 12-16
  • Change in model for end-stage liver disease score at two weeks, as an indicator of mortality or liver transplantation at 60 days in acute-on-chronic liver failure. Kumar R, Krishnamoorthy TL, Tan HK, Lui HF, Chow WC.
  • Gastroenterol Rep (Oxf). 2015 May;3(2):122-7
  • Can We Predict Sustained Virologic Response to Interferon a Therapy in Patients With Chronic Hepatitis Delta Virus Infection? Clin Gastroenterol Hepatol. 2015 Aug 5. Scholtes C, Kumar R , Zoulim F.
  • Clinical relevance of cccDNA- Liver international (Jan2016) Rajneesh Kumar , Sofía Pérez-del-Pulgar , Barbara Testoni , Fanny Lebossé, Fabien Zoulim 
  • Chronic Hepatitis B and fatty liver- Issues in clinical management. Clinics and  research in Hepatology and Gastroenterology,  Feb 2016, 
  • Development of hepatocellular carcinoma in chronic hepatitis B patients with advanced fibrosis is independent of viral genotype. Kumar R, Testoni B, Fresquet J, Lim TK, Hao Y, Tan HH, Chow WC, Zoulim F. J Med Virol. 2016 Oct 6. doi: 10.1002/jmv.24707
  • Real world experience with pegylated interferon and ribavirin in hepatitis C genotype 1 population with favourable IL28B polymorphism  Victoria Ekstrom; Rajneesh Kumar; Yi Zhao; Mei Ling Yee; Cynthia Sung; Dorothy Toh; Poh Yen Loh; Jessica Tan; Eng Kiong Teo; Wan Cheng Chow
  • Gastroenterology Report 2016; doi: 10.1093/gastro/gow033
  • Hepatitis B and concomitant hepatic steatosis. Ann Transl Med. 2017 Feb;5(3):38. doi: 10.21037/atm.2016.12.04 Lim CT, Kumar R

Abstracts and Oral presentations

  • ROLE OF THERAPEUTIC ERCP IN RPC ( NZ gastro scientific meeting 2012);R Kumar, N Vikneswaran, S J Mesenas
  • Utility of an immunoblot assay to detect a past Helicobacter pylori infection (APDW 2010); Rajneesh Kumar, Wang Yu Tien, Lim Gek Keow, Ling Khoon Lin
  • Does Endoscopic Ultrasound Influence the Management of Pancreatic Cystic Lesions? An Asian Multicentre Study ( APDW 2010); Ho Khek Yu, Sandeep Lakhtakia, Ang Tiing Leong, Charles K F Vu, Jennifer Shin, Frederick DY, Chong Vui Heng, Thawatchai Akaraviputh, Pradermchai Kongkam, Christopher Khor, Steven Mesenas, Jonard Tan, Rajneesh Kumar, Lim Wee Chian, Bhavesh Kishor Doshi, Salim Omar, Sharmila Sachitanandan, George Abraham, Taya Kitiyakara, Thawee Rantachu, Mathew Philips and the ASIAN EUS Research Forum
  • Identification of Prolactin,MCP-1 and angiostatin as potential Tumor markers in Hepatocellular carcinoma ( AASLD 2012) Rajneesh Kumar, Soo-Fan Ang, Who-Whong Wang, Hui-Hua Li, BBG Goh, Su-Pin Choo, Wan-Cheng Chow, Han-Chong Toh, Chee-Kiat Tan
  • Hepatitis B response to treatment in hepatic steatosis (APDW 2011) Rajneesh Kumar, HH Tan, KH Lim, WC Chow
  • Acute on Chronic Liver Failure in SGH (APDW 2011) Tan H K, Kumar R, Lui H F, Chow WC
  • Serum MCP-1, Prolactin, TIMP-4 and I-TAC identified as potential biomarkers in early-stage HCC (Duke –singhealth scientific meeting 2012) ;Chermaine Heah, Soo-Fan Ang, Who-Whong Wang,R Kumar, CheeKiat Tan, Han-Chong Toh, 
  • Adherence to surveillance poor in Chronic Liver Disease presenting as Acute on Chronic Liver Failure – Single Centre Experience (APASL 2014) Rajneesh Kumar, Thinesh Lee Krishnamoorthy, Tan Hiang Keat, Lui Hock Foong, Chow Wan Cheng
  • Predictors of adverse eventsat 60 days in Acute on chronic liver failure- A single tertiary centre experience (APASL 2014) Rajneesh Kumar, Thinesh Lee Krishnamo0rthy, Tan Hinag Keat, Lui Hock Foong, Chow Wan Cheng
  • Change in MELD after 2 weeks of acute on chronic liver failure as indicator of mortality or liver transplant at 60 days. (EASL2014) Rajneesh Kumar, Thinesh Lee Krishnamoorthy, Tan Hinag Keat, Lui Hock Foong, Chow Wan Cheng
  • Cost-Effectiveness of Pegylated Interferon and Ribavirin combination in treating Gentoype 1 Hepatitis C patients in Singapore. Victoria Sze Min Ekstrom, Mee Ling Yee, Wan Cheng Chow, Rajneesh Kumar –APASL 2015,
  • Successful Treatment Of Post Renal Transplant Hepatitis C With Sofusbuvir 
  • And Simeprevir (APASL 2015) Ennaliza Salazar, Rajneesh Kumar, Terence Kee, Chow Wan Cheng
  • Acceptability and Feasibility of a Nurse-Led Hepatitis B Tele-monitoring Service (NHMS) at Singapore General Hospital (SGH) K.D. Balasubramaniam, G.B.B. Goh, P.Y. Chia, X. Xin, X. Choi, K.L. Loy , R. Kumar, W.C. Chow- IHI ,Orlando, Dec 2015
  • IL28B polymorphism and ITPA gene variations in Hepatitis C genotype 1 patients treated with Pegylated Interferon and Ribavirin  Ekstr?m VSM, Kumar R, Zhao Y, Yee ML, Chow WC     (.APDW 2015)
  • Similar intrahepatic, serum virus-load and HCC in Hepatitis B genotype B&C with advanced fibrosis  (APASL 2016 ) Rajneesh Kumar ,Barbara Testoni, Judith Fresquet, Tony Kiat-Hon Lim, Wan Cheng Chow, Fabien Zoulim
  • Diabetes mellitus and not hepatic steatosis alone increases the risk of adverse events in patients with chronic hepatitis B. Kumar Rajneesh ,  Leow Wei-Qiang,  Lim Kiat-Hon Tony , A zhar Rafay , Wan Wei-Keat,  Chow Wan-Cheng, Goh Boon-Bee George UEGW , Vienna 2016
  • Prevalence of Hepatitis C virus infection and the IL28B genotype in the affected populations of Singapore APASL 2017 Shanghai , Benjy Soh Yi Min, Rajneesh Kumar , Victoria Ekstrom, Clement Lin,Sobana d/o Thangaraju, Hwee Huang Tan , Lina Hui Lin Chung, Diana Teo, Chow Wan Cheng
  • Natural History of Concomitant Chronic Hepatitis B and Hepatic Steatosis: A Longitudinal Cohort Analysis of 538 Patients Followed Up Over 12 Years APDW 2016, Gan TM, Kumar R, Lin YH, Lin WC, Chang PE , Tan CK, Goh GB

Oral Presentation

  • Is nurse-led virtual monitoring of chronic hepatitis B patients a safe, feasible and cost-effective complement to standard care  AASLD Boston, 2016

Research Trials