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Assoc Prof Lee Haur Yueh

Assoc Prof Lee Haur Yueh

MBBS, MRCP (UK), M Med (Int Med), FAMS (Dermatology)

Head & Senior Consultant

Director, Allergy Centre

Specialty: Dermatology

Sub-specialties: Dermatology, Allergic Skin Disease, Autoimmune Skin Disease, Drug Allergy

Clinical Appointments

  • Head & Senior Consultant Dermatology Singapore General HospitalSingapore General Hospital

Profile

Dr Lee graduated from the National Unviersity of Singapore and obtained his membership in the Royal College of Physicians in 2005.  He completed his specialty training in Dermatology in 2010.  

His subspecialty interests include cutaneous adverse drug reactions, autoimmune blistering diseases, and medical dermatology.  He has undergone further subspecialty in these areas at the Hopital Henri-Mondor, Assistance Publique-Hopitaux de Paris, France; Inselspital, Bern, Switzerland as well as King’s College Hospital, London, UK.

Education

  • MBBS, NUS
  • MRCP (UK)
  • M Med (Int Med)
  • FAMS (Dermatology)

Professional Appointments and Committee Memberships

  • Adjunct Associate Professor, Duke-NUS Medical School
  • Clinical Senior Lecturer, NUS Yong Loo Lin School of Medicine
  • Member, Residency Advisory Committee (Dermatology), MOH
  • Vice President, Dermatological Society of Singapore 

Awards

  • Outstanding Faculty, Singhealth RISE Awards (2015)
  • SingHealth Publish! Award (2013,2014)
  • SingHealth HMDP award for fellowship in cutaneous adverse drug reactions, immunobullous dermatology and hospital dermatology (2010)
  • Top Candiate – Dermatology Exit Exam, Chapter of Dermatology (2010)
  • SingHealth Talent Development Grant Award (2008)
  • Brunel Hayes Gold Medalist for Clinical Medicine – Final Professional Examination
  • Dean’s List 2nd / Final Professional Examination (2001, 2002) 

Research Interests

Publications

  1. Wang YH, Chen CB, Tassaneeyakul W, Saito Y, Choon SE, Lee HY, Chang M, Roa F et al.  The medication risk of Stevens-Johnson syndrome and Toxic Epidermal Necrolysis in Asians: the Major Drug Causality and Comparison to the USA FDA label.  Clin Pharmacol Ther 2019;105:112-20
  2. DCW Aw, EH Tan, TM Chin, HL Lim, HY Lee, RA Soo.  Management of epidermal growth factor receptor tyrosine kinase inhibitor-related cutaneous and gastrointestinal toxicities.  Asia Pac J Clin Oncol 2018;14:23-31
  3. HY Lee, S Fook-Chong, HY Koh, T Thirumoorthy, SM Pang. Cyclosporine treatment for Stevens-Johnson syndrome/toxic epidermal necroysis:  Retrospective analysis of a cohort treated in a specialized centre. J Am Acad Dermatol 2017  7;76:101-113
  4. Lee HY, Walsh SA, Creamer D.  Long term complications of Stevens-Johnson syndrome/toxic epidermal necrolysis: The spectrum of chronic problems in patients who survive an episode of SJS/TEN necessitates multi-disciplinary follow p.  Br J Dermatol 2017;177:924-35
  5. KT Amber, Lambers A, Soliman F, Agnoleti A, Didona D, Euverman I, Cozzani E, Lee HY et al.  Determining the incidence of Pneumocytis Pneumonia in Patients with Autoimmune Blistrig Diseases not receiving routine prophylaxis.  JAMA Dermatol 2017;11:1137-41
  6. Tan Koi WC, Sung C, Chong YY, Lateef A, Pang SM, Vasudevan A, Aw D, Lui NL, Lee SX, Ren EC, Koay ES, Tay YK, Lim YL, Lee HY et al.  Tailoring of recommendations to reduce severe cutaneous adverse drug reactions : a pharmacogenomics approach.  Pharmacogenomics 2017 18:881-90 
  7. Sim B, Fook-Chong S, Phoon TYW, Koh HY, Thirumoorthy T, Pang SM, Lee HY.  Multimorbidity in Bullous Pemphigoid: a case-control analysis of BP patients with age and gender matched controls.  J Eur Acad Dermatol Venereol 2017 ;31:1709-14
  8. Saw S, Lee HY, Ng QS.  Pembolizumab-induced Stevens-Johnson syndrome in non-melanoma patients. Eur J Cancer 2017;81:237-9
  9. Tan CW, Pang Y, Sim B, Thirumoorthy T, Pang SM, Lee HY. The association between drugs and bullous pemphigoid.  Br J Dermatol 2017 176;549-551
  10. Creamer D, Walsh SA, Dziewulski P, Exton LS, Lee HY et al.  UK Guidelines for the management of Stevens-Johnson syndrome/toxic epidermal necrolysis in adults 2016.  Br J Dermatol 2016;174:1194-227
  11. Lee HY, MX Shen, YL Lim et al. Increased risk of strontium ranelate-related SJS/TEN is associated with HLA.  Osteoporos Int 2016;27:2577-83
  12. Oh CC, Lee HY, Chan MF, Gopalakrishnan SK.  Treatment of overlap cutaneous graft-versus host disease with combination therapy of extracorporeal photophereis and alemtuzumab. Int J Dermatol 2016;55:335-8
  13. Heng YK, HY Lee, JC Roujeau. Epidermal necrolysis: 60 years of errors and advance. Br J Dermatol 2015;173:1250-4
  14. Phoon YW, Fook-Chong SM, Koh HY, Thirumoorthy T, Pang SM, Lee HY. Infectious complications in bullous pemphigoid: an analysis of risk factors.  J Am Acad Dermatol 2015;72:834-9
  15. Tay EY, Fook-Chong S, Oh CC, Thirumoorthy T, Pang SM, Lee HY.  Cellulitis Recurrence Score :  A tool for predicting recurrence of lower limb cellulitis. J Am Acad Dermatol 2015;72:140-5
  16. Tay EY, Busmanis I, Lee HY. Blistering eruption of the buttocks.  JAMA Dermatol 2015;451:1367-8
  17. Tay EY, Thirumoorthy T, Pang SM, Lee HY.  Clinical outcomes of bacteremia in cellulitis of the leg.  Clin Exp Dermatol 2014; 39:683-8
  18. Toh DS, Tan LL, Aw DC, Pang SM, Lim SH, Thirumoorthy T, Lee HY et al.  Building pharmacogenetics into a pharmacovigilance program in Singapore: using serious skin rash as a pilot study.  Pharmacogenomics J 2014;14:316-21
  19. Oh CC, Ko HC, Lee HY, Safdar N, Maki DG, Chlebicki MP.  Antibiotics prophylaxis for preventing recurrent cellulitis: A systematic review and meta-analysis. J Infect 2014;69:26-34
  20. HY Lee, Lim YL, Thirumoorthy T, Pang SM.  The role of intravenous immunoglobulin in toxic epidermal necrolysis:  a retrospective analysis of 64 patients managed in a specialized centre.  Br J Dermatol 2013;169:1304-9
  21. HY Lee, WH Chung.  Toxic epidermal necrolysis : Year in review.  Curr Opin Allergy Clin Immunol 2013;13:330-6
  22. Lee HY, Philippidou M, Schey S, Selway R, Walsh S, Creamer D.  Flexural eruption in two hospitalized patients.  Clin Exp Dermatol 2013 38;943-5
  23. HY Lee, Dunant A, Sekula P, Mockenhaupt M, Wolkenstein P, Valerie-Allanore L, Naldi L, Halevy S, Roujeau JC.  The role of prior corticosteroids on the clinical course of Stevens-Johnson syndrome and toxic epidermal necrolysis:  A case-control analysis of patients selected from the multi-national EuroSCAR and RegiSCAR studies.  Br J Dermatol 2012 Sep;167(3):555-62
  24. HY Lee, Philipidou M, Walsh S. Creamer D.  Sequential Stevens-Johnson syndrome and photo-recall phenomenon.  Br J Dermatol 2012;166(5):1145-6
  25. HY Lee, WY Chay, MBY Tang, M Chio, SH Tan.  Melanoma: Differences between Asian and Caucasian Patients.  Ann Acad Med Singapore 2012;41:17-20 

Book Chapters 
Ardern-Jones M, Lee HY.  Benign cutaneous adverse drug reactions to drugs. Chapter 118  Rook’s Textbook of Dermatology, 9th Edition, (Eds:  Griffith C, Barker J, Bleiker T, Chalmers R, Creamer D); Wiley 2016

Walsh S, Lee HY, Creamer D.  Severe cutaneous adverse drug reactions to drugs. Chapter 119. Rook’s Textbook of Dermatology, 9th Edition, (Eds:  Griffith C, Barker J, Bleiker T, Chalmers R, Creamer D); Wiley 2016 




Research Trials