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Dr Lao Zhentang

Dr Lao Zhentang

​MBBS, MRCP(UK)

Senior Consultant

Singapore General Hospital

Specialty: Haematology

Sub-specialties: Acute Leukemia

Conditions Treated by this Doctor:
Acute Lymphocytic Leukemia (ALL), Aplastic Anaemia, Chronic lymphocytic leukemia, Chronic Myeloid Leukemia (CML), Deep Vein Thrombosis, Deep Vein Thrombosis, essential thrombocythemia, Multiple Myeloma, Myelodysplastic Syndromes, Myelofibrosis, Polycythemia Vera, Pulmonary Embolism, Thalassaemia.

Clinical Appointments

  • Senior Consultant SingHealth Duke-NUS Blood Cancer Centre
  • Senior Consultant Haematology Singapore General HospitalSingapore General Hospital

Profile

Dr Lao graduated from the National University of Singapore, School of Medicine in 2007. He obtained his haematology specialist accredited in 2017. His areas of interest are acute leukemia and genetics of myeloid malignancies. He was awarded NRMC Research Fellowship to support his research development in 2017 and has completed his PhD. 

Education

Professional Appointments and Committee Memberships

  • ​Clinical Lecturer - NUS YLL School of Medicine
  • Clinical Assistant Professor – Duke-NUS School of Medicine 


Awards

  • ​NRMC Research Fellowship (PhD)
  • Singhealth Best Registrar Award (2015)

Research Interests

  • ​Myeloid malignancy
  • Cancer genomics and epigenomics

Publications

  • Kolla BC, Halim NAA, Cao Q, Sachs Z, Warlick E, Weisdorf D, et al. High risk of relapse with intermediate dose cytarabine for consolidation in young favourable-risk acute myeloid leukaemia patients following induction with 7+3: a retrospective multicentre analysis and critical review of the literature. Br J Haematol. 2021 Jul;194(1):140–4. 
  • Sun Q-Y, Ding L-W, Johnson K, Zhou S, Tyner JW, Yang H, et al. SOX7 regulates MAPK/ERK-BIM mediated apoptosis in cancer cells. Oncogene. 2019 Aug;38(34):6196–210. 
  • Lao Z-T, Ding L-W, An O, Hattori N, Sun Q-Y, Tan K-T, et al. Mutational and transcriptomic profiling of acute leukemia of ambiguous lineage reveals obscure but clinically important lineage bias. Vol. 104, Haematologica. 2019. p. e200–3. 
  • Ding L-W, Tan K-T, Sun Q-Y, Lao Z-T, Yang H, Jiang N, et al. Clonality and clonal evolution analysis of paediatric ALL based on B-cell receptor/T-cell receptor rearrangement. Vol. 184, British journal of haematology. England; 2019. p. 829–33. 
  • Tan K-T, Ding L-W, Sun Q-Y, Lao Z-T, Chien W, Ren X, et al. Profiling the B/T cell receptor repertoire of lymphocyte derived cell lines. BMC Cancer. 2018 Oct;18(1):940. 
  • Ding L-W, Sun Q-Y, Mayakonda A, Tan K-T, Chien W, Lin D-C, et al. Mutational profiling of acute lymphoblastic leukemia with testicular relapse. Vol. 10, Journal of hematology & oncology. 2017. p. 65. 
  • Lao Z, Yiu R, Wong GC, Ho A. Treatment of elderly patients with acute myeloid leukemia with azacitidine results in fewer hospitalization days and infective complications but similar survival compared with intensive chemotherapy. Asia Pac J Clin Oncol. 2015 Mar;11(1):54–61. 
  • Koh MBC, Lao ZT, Rhodes E. Managing haematological disorders during pregnancy. Best Pract Res Clin Obstet Gynaecol. 2013 Dec;27(6):855–65.

Research Trials