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Zidovudine

Drug Class: Commonly Known As: Category:
Antiretroviral Agent Retrovir™ Adult, Children

Zidovudine - What is it for

Zidovudine is an antiretroviral agent that blocks construction of virus. It is used to decrease the amount of viruses (viral load) to as low as possible, for as long as possible.

Zidovudine - Side Effects, Precautions, and Contraindications

What side effects can Zidovudine cause?

Common side effects include:

  • Diarrhea, nausea and vomiting. This can be prevented by eating small frequent meals or sucking on candy.
  • Headache and pain. Mild painkillers (e.g. paracetamol) can be taken to reduce the pain.
  • Dizziness. Do not drive or operate machinery
  • Anorexia
  • Fever
  • Fatigue/tiredness
  • Skin rash
  • Insomnia, sleep disturbances.

Inform your doctor if the side effects become severe and bothersome.

Report to the doctor immediately if your child complains of numbness or tingling of fingers, toes or feet.

Before taking Zidovudine, what precautions must I follow?

What food or medicine must I avoid when I take Zidovudine?

Zidovudine - Dosage and How to Use

How should Zidovudine be used?

Zidovudine is usually taken 2 to 3 times daily, with or without food.

It is usually given in combination with at least two other antiretroviral agents.

Zidovudine may be given alone to new-born babies of HIV-infected mother to reduce the risk of infection.

What should I do if I miss a dose?

Missing doses make Zidovudine less effective and may also make the virus resistant to Zidovudine and other possible antiretroviral agents.

If you forget to take a dose, don’t worry. You can take your next dose as soon as you remember but not within two hours of your next dose. If you remember within two hours of your next dose, just skip the dose you missed and take your next dose at the usual time. Then continue your treatment as before.

Don’t take a double dose to make up for a missed dose.

If your child vomits within 15 minutes of administration, give another dose as possible.

What should I do if I overdose?

Zidovudine - Handling and Storage

How should I handle Zidovudine safely?

How should I store Zidovudine?

Keep away from children;#Keep in a cool, dry place, away from direct sunlight;#Store at room temperature;#

How should I dispose of Zidovudine safely?

Zidovudine - Additional Information

Some medication may reduce its efficacy, or increase its toxicity. Do not give your child any other medications or herbal products without first consulting your doctor.

  • Updated on Wednesday, September 27, 2017
  • Article contributed by Pharmacy Department KK Women's and Children's Hospital

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