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Mesalazine

Drug Class: Commonly Known As: Category:
Aminosalicylic Acid

Mesalazine - What is it for

​This medication is used for the treatment of various inflammatory conditions of the gastrointestinal tract including ulcerative colitis and Crohn’s disease.

Mesalazine - Side Effects, Precautions, and Contraindications

What side effects can Mesalazine cause?

​Common side effects of this medication include gastrointestinal discomfort, nausea and vomiting, diarrhoea, headaches, muscle pain, reduced appetite and a cough. If symptoms persist or cause significant discomfort, please consult your healthcare professional.

Some Rare but Serious Side Effects:

This medication may affect the blood particularly in the first few months of treatment. Report to your healthcare professional any unexplained bleeding, bruising, sore throat, fever or malaise that occur during treatment. You may be required to have your blood checked at intervals while taking this medication.

This medication may affect the liver. Report to your healthcare professional signs of liver problems including persistent dark urine or light coloured stool with abdominal discomfort and nausea and vomiting and/or yellowing of the skin or eyes. Your healthcare professional will require you to have your blood checked at intervals to monitor your liver.

This medication may affect the kidney. Inform your healthcare professional if you are passing less or no urine or if there is blood in the urine.

The symptoms of a drug allergy include one or more of the following:

  • Swollen face/eyes/lips/tongue
  • Difficulty in breathing
  • Itchy skin rashes over your whole body

If you experience any of these symptoms, you should stop your medication and see your healthcare professional immediately.

Before taking Mesalazine, what precautions must I follow?

​Inform your healthcare professional if:

  • You are allergic to this medication or any of the other ingredients of this medication.
  • You are pregnant, planning to become pregnant, or breastfeeding.
  • You are taking any other medications, including supplements, traditional medications and herbal remedies.
  • You have a history of liver or kidney disease.

What food or medicine must I avoid when I take Mesalazine?

Inform your healthcare professional if you are taking or intend to take any other medications, including supplements, traditional medications and herbal remedies.

Mesalazine - Dosage and How to Use

How should Mesalazine be used?

  • ​Do not stop taking your medication without checking with your healthcare professional.
  • This medication may be administered by mouth (e.g. as tablets or granules) or rectally (e.g. as an enema or suppository).
  • Some preparations taken by mouth should be taken before food while others can be taken irrespective of food. Please check with your healthcare professional with respect to the specific preparation.
  • Some modified or slow release or enteric coated preparations taken by mouth should be swallowed whole, not chewed or crushed. If uncertain, please consult your healthcare professional.
  • Consult your healthcare professional with respect to how to administer rectal preparations.

What should I do if I miss a dose?

​If you forget to take a dose, take it as soon as you remember. Then take your next dose at the usual time. If it is close to the time for your next dose, skip the missed dose and go back to your normal administration time. Do not take two doses to make up for the missed dose.

What should I do if I overdose?

Mesalazine - Handling

How should I handle Mesalazine safely?

Mesalazine - Storage

How should I store Mesalazine?

Keep away from children;#Keep in a cool, dry place, away from direct sunlight;#

How should I dispose of Mesalazine safely?

​Pack this medication into a black trash bag and seal it tightly before throwing into the rubbish chute or bin.

Mesalazine - Additional Information

  • Updated on Sunday, January 31, 2021
  • Article contributed by PSS National Medication Information Workgroup PSS National Medication Information Workgroup

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