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Deferasirox

Drug Class: Commonly Known As: Category:
Iron chelators Jadenu Adult, Children

Deferasirox - What is it for

Deferasirox is indicated for the treatment of chronic iron overload due to frequent blood transfusions or non-transfusion dependent thalassemia syndromes.

Deferasirox - Side Effects, Precautions, and Contraindications

What side effects can Deferasirox cause?

  1. Nausea, vomiting
  2. Diarrhoea, stomach pain, bloating, constipation, indigestion
  3. Headache
  4. Rash
  5. Kidney problems
  6. Liver problems

Inform your doctor if any of the following occurs:

  1. Severe rash or difficulty breathing and dizziness, or swelling of the face and throat
  2. Severe rash, red skin, blistering of lips, eyes or mouth, skin peeling, sore throat
  3. Marked decrease in urine output
  4. Drowsiness, upper right abdominal pain, yellowing of skin or eyes and dark urine
  5. Vomiting blood or black stools
  6. Frequent abdominal pain
  7. Severe upper stomach pain (pancreatitis)
  8. Partial vision loss or decreased hearing

Before taking Deferasirox, what precautions must I follow?

Talk to your doctor before taking Desferasirox:

  1. If you have any problems with your liver or kidneys
  2. If you are pregnant or planning to become pregnant
  3. If you are breast-feeding. Do not breast-feed while you take this drug and for 1 week after your last dose
  4. If you are taking or recently taken any other medications

What food or medicine must I avoid when I take Deferasirox?

Tell your doctor or pharmacist the medicines you are taking including antacids (medicine used to treat heartburn), certain painkillers or anti-inflammatory medicines.

Deferasirox - Dosage and How to Use

How should Deferasirox be used?

Deferasirox should be taken orally as prescribed by your doctor. It may be taken on an empty stomach or with a light meal. Tablets can be swallowed whole with some water.

For patients who are unable to swallow whole tablets, it may be crushed and administered by sprinkling onto soft food (e.g. yogurt), consume immediately

Do not take together with aluminium-containing medications or supplements.

What should I do if I miss a dose?

If you miss a dose, take the missed dose as soon as you remember it, even if it is later in the day. Take your next dose as scheduled.

Do not take two doses at once or take extra doses on the next day to make up for the forgotten tablets.

What should I do if I overdose?

If you overdose on this medicine, inform your doctor immediately.

Deferasirox - Handling

How should I handle Deferasirox safely?

​No extra handling precautions.

Deferasirox - Storage

How should I store Deferasirox?

Keep away from children;#Keep in a cool, dry place, away from direct sunlight;#Store at room temperature;#

How should I dispose of Deferasirox safely?

Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs.

Deferasirox - Additional Information

  • Updated on Wednesday, May 15, 2019
  • Article contributed by Pharmacy Singapore General Hospital

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