Your generous support will help our clinician scientists translate meaningful scientific discoveries into quality innovations in patient treatment and care, and spur our clinician educators to build on the legacy of esteemed physicians in passing their knowledge on to the next generation.

1 in 10 people suffers from Rheumatological diseases in Singapore. There are more than 30 different chronic and complex Rheumatological diseases that can affect major organs like the joints, heart, lungs, kidneys and skin, causing serious complications which can be life-threatening. Currently, there is no cure. Despite scientific breakthroughs in the past decades, little is known about the exact causes of Rheumatological diseases. Diagnosis is difficult and as a result, often delayed. Treatment options are limited and in some cases, there are none - symptoms can only be managed. Your gift towards the Reverie Rheumatology Research Fund (RRRF) Endowed Fund enable progress in 5 key areas namely the Osteoarthritis, Rheumatoid Arthritis, Systemic Lupus Erythematosus, Spondyloarthritis and Systemic Sclerosis: 1. Expedite research into predicting diseases flares and progress; 2. Develop and test new effective treatments; 3. Nurture and sustain a core of trained and committed research team; 4. Fund novel pilot research projects which, if successful, would provide the basis to apply for larger research grant funds to continue this research.

Singapore has one of the highest incidence of patients with End Stage Renal Disease (complete failure of the kidneys) in the world. Every day, 4 patients start their costly dialysis treatments and this growing number of patients remain at risk with possibility of heart attacks, strokes and infection. This lifelong medical condition brings much emotional and financial burden to our patients and their families. They need help. 100% of your valuable gift towards the ARK (Advancing Resources for Kidney Diseases) will help ensure that renal patients receive the appropriate holistic medical care - from prevention, timely diagnosis to treatments. Your gift build sustained efforts to • Develop and test new effective treatments; • Expedite research to detect and predict the progression of disease; • Nurture healthcare workers to bring the best patient outcomes for renal patients; • Fund novel pilot research projects and aim to apply for larger research grant funds to continue and expand the research. Your support will enable progress in four strategic areas: • Prevention through screening and timely diagnosis; • Reno-retardation programme to slow down progression of illness; • Kidney transplant; • Renal replacement therapies

Pathology underpins every facet of disease diagnosis and treatment and plays a crucial role in patient care. Every individual who has consulted a medical doctor would have come into contact with pathology services, through blood, fluid or tissue samples analysed by a pathologist. As our invisible doctors, pathologists play a vital role in providing accurate and reliable diagnoses so that our patients can receive appropriate and timely care. Our doctors do not work in silos and are ably supported by our teams, who work tirelessly to ensure all samples are analysed accurately. Since our humble beginnings as a bacteriologist-led laboratory back in 1903, SingHealth Pathology has evolved into multidisciplinary pathology specialties with Signature Research Programmes (in breast cancer and fibroepithelial lesions, microbiological investigations in disease outbreaks and infections, prognostication of chronic liver disease, and childhood cancer) that have led to significant healthcare breakthroughs. We believe more can be done. Every dollar of your generous gift will aid our relentless endeavours to fight diseases, find the right diagnosis and pave the way to discover better cures for improved patient care outcomes.

Every year, 100 children in Singapore are born with congenital malformations and newborn diseases, where natural body organs fail to develop properly at birth. Despite surgical attempts to reconstruct or substitute various defects, many succumb to respiratory, intestinal or kidney failure, or are left with life-long disabilities. Your generous support will increase the survival of children with these disorders from birth (after 40 weeks’ of pregnancy) to adulthood (40 years), and decrease the burden of long-term disability through research and education in the following areas: 1. Predictive testing methods to identify patients at highest risk of deterioration and disability. 2. Technologies to improve the quality of surgical correction of congenital malformations and newborn diseases. 3. Supportive care systems to alleviate the burden of disability in incurable disorders. About 300 children with various congenital disorders will benefit each year. Our education initiatives will share knowledge and new discoveries with medical professionals, parents and families locally and regionally too. 100% of your gift towards this key initiative under SingHealth Surgery Academic Clinical Programme resides in SGH Health Development Fund. Your support will help save more children, such as Ally*, who was born with a rare condition called cloacal exstrophy. Ally had more than 10 reconstructive surgeries since she was a baby. In primary school now, she enjoys singing and aspires to be a surgeon – just like those who helped made her life better. Your generosity gives hope to parents and families, and enables our children to dream a little dream. Another beneficiary is baby Lyn, who was born with esophageal atresia – a condition where her throat was not connected to her stomach. Lyn is growing up 'normally' today after four major operations and multiple minor procedures. Will you lend help and give hope to children like Ally and Lyn? *not their real names