Clin Asst Prof Ennaliza Salazar

I am a gastroenterologist with a special interest in clinical nutrition and inflammatory bowel disease. In 2019, I completed a clinical fellowship at Toronto General Hospital, Canada. Following this, I returned to Singapore and have been involved in developing and strengthening the home parenteral nutrition programme and broader clinical nutrition services at Singapore General Hospital. We maintain prospective registries for both home and inpatient parenteral nutrition. My academic interests include clinical research in nutrition and inflammatory bowel disease, and I have successfully secured research funding to support work in these areas.

• MBCHB
• MPH candidate

• Director of Nutrition Support Service, Singapore General Hospital since 2016
• Physician Faculty member, SInghealth Gastroenterology and Hepatology Residency Program since 2016
• Chairperson for National Foundation For Digestive Disease since 2021
• Committee member of Singapore Chapter of International Intestinal Rehabilitation and Transplantation since 2025
• Committee member of Gastroenterological Society of Singapore Since 2025
• Committee member in Society for Parenteral And Enteral Nutrition ( Singapore ) from 2023-2025

1. Tan YY, Cheong EHT, Lim CT, Cai S, Tay SW, Leong JWH, Salazar E, Cheng LT, Low ASC, Tan MTK. Clinical and environmental impact of intestinal ultrasound for inflammatory bowel disease: a tertiary centre experience in Southeast Asia. Scand J Gastroenterol. 2025 Sep;60(9):889-899. doi: 10.1080/00365521.2025.2533338.
2. Lim SJM, Chen K, Tan YY, Tay SW, Lim TCT, Salazar E, Chan WP, Tan MTK. Early predictors of rescue therapy and colectomy in acute severe ulcerative colitis. Singapore Med J. 2025 Aug 1;66(8):449-456. doi: 10.4103/singaporemedj.SMJ-2024-242.
3. Lee YS, Zulkifli N, Lim YH, Lim SYY, Chow BJW, Salazar E, Wong SM. The Impact of Home Enteral Tube-Feeding on the Intent and Experience of Going Out in Public: A Qualitative Study on Patients' and Caregivers' Perspectives. J Hum Nutr Diet. 2025 Feb;38(1):e70018. doi: 10.1111/jhn.70018.
4. Qui M, Salazar E. Beyond Suppression: Peripheral T Cell Responses to Vaccination in Inflammatory Bowel Disease Patients Undergoing Anti-Tumor-Necrosis-Factor Therapy. Vaccines (Basel). 2024 Nov 14;12(11):1280. doi: 10.3390/vaccines12111280.
5. Lim CT, Tay SW, Elangovan S, Ong WC, Lim GH, Salazar E, Chan WPW, Tan MTK. Long-term effectiveness and persistence rate of ustekinumab dose intensification in a South East Asian inflammatory bowel disease center. J Gastroenterol Hepatol. 2024 Aug;39(8):1544-1553. doi: 10.1111/jgh.16562.
6. .Cheang L Y, Chong JCN, Poh BY, Lee BT, Goh JLR, Lee MS, Tan TCK, Hanis AK, Cheah CCM, Salazar E. Approximately 50% of acute intestinal failure ( AIF) patients on short term parenteral nutrition have intestinal failure associated liver disease without effect of hospital length of stay and mortality. Clin Nutr ESPEN. 2024 Jun;61:140-144. DOI: https://www.clinicalnutritionespen.com/article/S2405-4577(24)00062-7/abstract
7. Kang G, Chuen MCC, Yen PB, Boo TL, Choo JCN, Ye CL, Goh Jia Ling R, Sim LM, Chye TTK, Salazar E. Parenteral nutrition- related complications in hospitalised elderly patients with acute intestinal failure: A descriptive cohort study. JPEN J Parenter Enteral Nutr. 2023 Nov 22. doi: 10.1002/jpen.2578..
8. B Sim, M C C Cheah, W P W Chan, Y T Wang, M T K Tan, H H Shim, E Salazar. Approximately 1 in 10 Ambulatory Inflammatory Bowel Disease Patients Are At Risk Of Malnutrition– A Prospective Singapore Cohort J Dig Dis. 2023 Jan;24(1):10-18. doi: 10.1111/1751-2980.13165
9. Soon JJY, Juan DWK, Ong WS, Bek S, Neo PSH, Salazar E, Da Zhuang K, Tan YP, Seo CJ, Ong JCA, Chia CS, Wong JSM. Implementation of a Multi-Disciplinary Team and Quality of Goals of Care Discussions in Palliative Surgical Oncology Patients. Ann Surg Oncol. 2023 Sep 6. doi: 10.1245/s10434-023-14190-z.
10. Cheah CCM, Ng HM, Chiou FK, Logarajah V, Salazar E. Long term clinical outcomes of home parenteral nutrition in Singapore. Asia Pac J Clin Nutr. 2023;32(2):282-294. doi: 10.6133/apjcn.202306_32(2).0011
11. Tan JYT, Cheah CCM, Wang YT, Chang PEJ, Krishnamoorthy TL, Tan HK, Salazar E. Outpatient screening with the Royal Free Hospital-Nutrition Prioritizing Tool for patients with cirrhosis at risk of malnutrition. Nutrition. 2023 Oct;114:112139. doi: 10.1016/j.nut.2023.112139
12. Yeo JQ, Cheen HHM, Wong A, Lim TG, Chowbay B, Leong WF, Wang C, Salazar EChan WPW, Kong SC, Ong WC. Clinical utility of thiopurine metabolite monitoring in inflammatory bowel disease and its impact on healthcare utilization in Singapore. JGH Open. 2022 Aug 1;6(10):658-666. doi: 10.1002/jgh3.12798.
13. Chan W, Wei LK, Tan T, Hsiang LG, Kong C, Salazar E, Koay D, Khor C, Asokkumar R. Motorized spiral enteroscopy versus double-balloon enteroscopy: a case-matched study. Gastrointest Endosc. 2023 Feb;97(2):314-324. doi: 10.1016/j.gie.2022.09.030. Epub 2022 Oct 11. PMID: 36228697.
14. Qui M, Le Bert N, Chan WPW, Tan M, Hang SK, Hariharaputran S, Sim JXY, Low JGH, Ng W, Wan WY, Ang TL, Bertoletti A, Salazar E. Favorable vaccine-induced SARS-CoV-2-specific T cell response profile in patients undergoing immune-modifying therapies. J Clin Invest. 2022 Jun 15;132(12):e159500. doi: 10.1172/JCI159500. PMID: 35536644; PMCID: PMC9197512.
15. Goh R J L, Li H, Cheah M C C, Salazar E .The use of standardized commercially available parenteral nutrition as a bridge to customized compounded bag in the acute hospital setting is safe and feasible
    Clin Nutr ESPEN 2022 Feb; 47: 321-324
16. Danese S, Colombel J F, Lukas M, Gibert J, D’Haens G, Hayee B, Panaccione R, Kim H S, Reinisch W, Tyrrell H, Oh Y S, Tole S, Chai A, Chamberlain-James K, Tang M T, Schreiber S, Gardenia Study Group. Etrolizumab versus infliximab for treatment of moderately to severey active ulcerative colitis ( Gardenia): a randomized double-blind, double dummy, phase 3 study
    Lancet 2022 Feb ; 7 (2): 118-127
17. Asokkumar R, Seow I, Lim C H, Chang J, Tan D, Salazar E . Rostered routine testing for severe acute respiratory coronavirus 2 infection among healthcare workers: Do we detect more?
    J Gastroenterol Hepatol Feb 2022 ; 37 (2): 404-405
18. Clermont-Dejean N M, Schwenger K J P, Salazar E, Colombo F F, Lu Z, Lou W, Gramlich L, Whittaker S, Armstrong , Jurewitsch B, Raman M, Duerksen D, Mchattie J, Allarp J P.Home parenteral nutrition patients on mixed oil lipid emulsion have a higher number of hospitalization than those on soybean oil- A prospective cohort studyClin Nutr. 2021 Jul;40(7):4616-4623. doi: 10.1016/j.clnu.2021.06.012. Epub 2021 Jun 17.PMID: 34229267
19. Chan W, Salazar E, Teong G L, Ong W C, Shim H H. Vaccinations and inflammatory bowel disease- a systematic review.
    Dig Liver Dis. 2021 Sep;53(9):1079-1088. doi: 10.1016/j.dld.2021.04.015. Epub 2021 May 11.PMID: 33994128
20. Salazar E, Alenezi S, Schwenger K J P, Casselman S, Somlaw N, Kim P, Adjemian D, Lu Z, Lou W, Ma D, Allard J P. Olive oil-based lipid emulsion is non inferior to soybean oil-based lipid emulsion in acute care setting: a double blind randomized controlled study.
    Nutrition. 2021 Sep;89:111283. doi: 10.1016/j.nut.2021.111283. Epub 2021 Apr 18.PMID: 34090216
21. Salazar E, Poh B Y, Cheang L Y, Tan L B, Yong P W, Cheah M C C. A modified minimal contact COVID-19 workflow allows for safe, remote , parenteral nutrition prescribing in non-critically ill patients. JPEN J Parenter Enteral Nutr. 2021 Aug;45(6):1364-1368. doi: 10.1002/jpen.2104. Epub 2021 Apr 20.
22. Leong WHJ, Tan XHA, Salazar E. More than Pus- Primary hepatic epithelioid angiomyolipoma masquerading as liver abscess. Case Rep Gastroenterol. 2021 Jan 8;15(1):1-8. doi: 10.1159/000511886. eCollection 2021 Jan-Apr.PMID: 33613156
23. Salazar E, Cheah MC C . Prescribing Parenteral nutrition in acute hospital setting during COVID-19: The Singapore Experience. Clin Nutr. 2020 Jul;39(7):2321. doi: 10.1016/j.clnu.2020.05.029. Epub 2020 May 30.
24. Salazar E, Clermont-Dejean N M, Schwenger K J P, Noelting J, Lu Z, Lou W, Allard J P.Patients with severe gastrointestinal dysmotility disorders receing parenteral nutrition have similar survival as those with short bowel syndrome: A Prospective Cohort Study.
    JPEN J Parenter Enteral Nutr. 2021 Mar;45(3):530-537. doi: 10.1002/jpen.1866. Epub 2020 Jun 4.PMID: 32383772
25. Asokkumar R, Salazar E.Nutrition training in residency and fellowship programme: time for a change.
    SInghealth Proceeding 2020
26. Soetikno R, Asokkumar R, Chin YK, Salazar E, Nguyen-Vu T, Sanduleanu S, Chang P E, Kaltenbach T. Rapid and safe crossing of the chasm: Application of a flipped learning framework for the clipping over the scope technique. New York. Elsevier Publisher. Available from endoscopic closure techniques: endoscopic clipping over the scope (C-OTS) and endoscopic suturing. Gastrointest Endosc Clin N Am. 2020 Jan;30(1):99-106. doi: 10.1016/j.giec.2019.09.002.
27. Salazar E, Ghosh P, Tan V, Pang T, Poh BY, Tan LB, Loy Kl, Chong J, Beh HL, Ng HM, Ling KL, Wang YT. Effect of alternative intravenous lipid emulsion in clinical outcome in non-critically ill patients.
    Clin Nutr ESPEN. 2019 Oct;33:42-46. doi: 10.1016/j.clnesp.2019.07.013. Epub 2019 Aug 2.PMID: 31451274
28. Wong YJ, Lum HM, Fook-Chong S, Lim ST, Salazar E.Do total parenteral nutrition and bowel rest reduce the risk for perforation in patients with gastrointestinal tract lymphoma receiving chemotherapy? Nutrition. 2019 Nov-Dec;67-68:110515. doi: 10.1016/j.nut.2019.03.023. Epub 2019 Jun 20
29. Salazar E, Sin EI, Low Y, Khor CJL.Insulated-tip knife- an alternative method of marsupializing a sympatomatic duodenal duplication cyst in a 3-year old child. VideoGIE. 2018 Sep 26;3(11):356-357. doi: 10.1016/j.vgie.2018.08.006. eCollection 2018 Nov
30. Asokkumar R, Soetikno R, Sanchez-Yague A, Lim K W, Salazar E, Ngu J H .The use of over-the-scope-clip ( OTSC) improves the outcomes of high-risk adverse outcome ( HR-AO) non variceal upper GI bleeding ( NVUGIB). Endosc Int Open. 2018 Jul;6(7):E789-E796. doi: 10.1055/a-0614-2390. Epub 2018 Jul 4.
31. Sin E I L , Salazar E, Khor C J L , Low Yee. Endoscopic decompression and marsupialization of a duodenal duplication cyst Journal of Paediatric Surgery Case report 2018
32. E. Salazar ,C K Tan, Goh BB .‘Broken heart’ in acute on-chronic liver failure.
    Proceeding of Singapore Healthcare 2016
33. Pandey A, Salazar E, Kong CSC, Lim WC, Ong EH, Ong C, Aw M, Wee E, Chuah SW, Ling KL The risk of major abdominal surgery in an Asian population-based crohn’s disease cohort. Inflamm Bowel Dis. 2015 Nov;21(11):2625-33. doi: 10.1097/MIB.0000000000000525.
34. Than NN, Ching DK, Hodson J, McDowell P, Mann J, Gupta R, Salazar E, Ngu JH, Oh YH. Difference in clinical presentation, immunology profile and treatment response of type 1 autoimmune hepatitis between United Kingdom and Singapore patients. Hepatol Int. 2016 Jul;10(4):673-9. doi: 10.1007/s12072-016-9727-4. Epub 2016 Apr 21