Profile
Dr. Bee is Head and Senior Consultant with the Department of Endocrinology at Singapore General Hospital (SGH) and Clinical Associate Professor at Duke-NUS Medical School, Singapore. He is also the Vice-President of Diabetes Singapore. Dr. Bee graduated from medical school at the National University of Singapore (NUS) and completed his specialist training in Endocrinology at SGH. In 2008, he was awarded the Health Manpower Development Plan (HMDP) fellowship by the Ministry of Health and spent the year training at the Joslin Diabetes Centre in Boston, USA.
Dr. Bee’s main clinical interest is in managing diabetes mellitus and lipid disorders. His academic research covers broad areas, including diabetes prevention, artificial intelligence-enabled risk prediction of diabetic complications and disease registries. He established the SingHealth Diabetes Registry (SDR) in 2016, a multi-institutional diabetes database built from SingHealth’s Electronic Medical Record system. He is also the Principal Investigator of the A*STAR-funded Diabetes Clinic of the Future (DCOF) programme, which aims to develop solutions using data analytics and digital technology to personalise care and improve outcomes for the multi-ethnic diabetes population in Singapore.
Education
- FRCP (Edin), Royal College of Physicians (Edinburgh)
- MRCP(UK), Royal College of Physicians (United Kingdom)
- MBBS, National University of Singapore
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Professional Appointments and Committee Memberships
- Vice-president, Diabetes Singapore
- Fellow, Royal College of Physicians, Edinburgh
- Member, Endocrine and Metabolic Society of Singapore
- Member, American Diabetes Association
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Awards
- SingHealth GCEO Excellence Award: Outstanding Researcher Award 2023
- SingHealth 20-Year Long Service Award 2019
- Singapore Health Quality Service Award 2017 (Gold award)
- Singapore Health Quality Service Award 2013 (Star award)
- SingHealth Health Manpower Development Plan (HMDP) Award 2008
- Service with a Heart Award (SGH) 2005, 2006, 2010, 2011, 2016
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Publications
- Bee YM, Batcagan-Abueg AP, Chei CL, Do YK, Haaland B, Goh SY, Lee PC, Chiam P, Ho E, Matchar D. A Smartphone Application to Deliver a Treat-to-Target Insulin Titration Algorithm in Insulin-Naive Patients With Type 2 Diabetes: A Pilot Randomized Controlled Trial. Diabetes Care 2016 Oct;39(10):e174-6. PMID: 27506223.
- Tan FCJH, Ang SB, Bee YM. Metformin use in patients with type 2 diabetes mellitus and chronic kidney disease: An evidence-based review. Ann Acad Med Singap. 2021 Feb;50(2):159-170. PMID: 33733259
- Lim DYZ, Chia SY, Hanis AK, Nur Nasyitah MS, Bee YM. Establishment of the SingHealth Diabetes Registry. Clinical Epidemiology 2021;13:215-223. PMID: 33762850
- Sun X*, Bee YM*, Lam SW, Liu Z, Zhao W, Chia SY, Abdul Kadir H, Wu JT, Ang BY, Liu N, Lei Z, Xu Z, Zhao T, Hu G, Xie G. Effective treatment recommendations for type 2 diabetes management using reinforcement learning: treatment recommendation model development and validation. J Med Internet Res. 2021 Jul 22:23(7):e27858. PMID: 34292166. *Joint first authors.
- Yeung KF, Gandhi M, Lam AYR, Julianty S, Chia AYM, Tan GCS, Goh SY, Ho ETL, Koh AFY, Tan GSW, Shum EJW, Finkelstein FA, Jafar TH, Teoh YL, van DAM RM, Whitton C, Thumboo J, Bee YM. The Pre-Diabetes Interventions and Continued Tracking to Ease-out Diabetes (Pre-DICTED) program: study protocol for a randomized controlled trial. Trials 2-21 Aug 6;22(1):522. PMID: 34362409.
- Amirruddin NS, Tan WX, Tan YS, Gardner, DSL, Bee YM, Verma CS, Hoon S, Lee KO, Teo AKK. Progressive endoplasmic reticulum stress over time due to human insulin gene mutation contributes to pancreatic beta cell dysfunction. Diabetologia 2021 Nov;64(11):2534-2549. PMID: 34448879.
- Feng L, Lam AYR, Carmody D, Lim CW, Tan GSW, Goh SY, Bee YM, Jafar TH. Trends in cardiovascular risk factors and treatment goals in patients with diabetes in Singapore – analysis of the SingHealth Diabetes Registry. PLoS One. 2021 Nov 8;16(11):e0259157. PMID: 34448879
- Bee YM, Tai ES, Wong TY. Singapore's "War on Diabetes". Lancet Diabetes & Endocrinology. 2022 Jun;10(6):391-392. PMID: 35483379
- Chan SP, Azizul HA, Bee YM, Deerochanawong C, Paz-Pacheco E, Tiu F, Foo SH, Tan KEK, Le TQ, Saraswati MR, Bunnag P, Sibarani RP, Raza SA, Tran NQ. Practical Guidance on Basal Insulin Initiation and Titration in Asia: A Delphi-based Consensus. Diabetes Therapeutics. 2022 Aug;13(8):1511-1529. PMID: 35767186
- Tan JK, M Salim NN, Lim GH, Chia SY, Thumboo J, Bee YM. Trends in diabetes-related complications in Singapore, 2013-2020: A registry-based study. PLoS One. 2022 Oct 11;17(10):e0275920. PMID: 36219616
- Yeung KF, Lee YQ, Chong MFF, Gandhi M, Lam AYR, Julianty S, Tan GCS, Ho ETL, Goh SY, Tan GSW, Shum EJW, Finkelstein EA, Jafar TH, van Dam RM, Teoh YL, Thumboo J, Bee YM. Baseline characteristics of participants in the Pre-Diabetes Interventions and Continued Tracking to Ease-out Diabetes (Pre-DICTED) Program. BMJ Open Diabetes Research and Care. 2022 Oct; 10(5):e002966. PMID: 36220198
- Tee C, Xu H, Fu X, Jafar TH, Bee YM. Longitudinal HbA1c trajectory modelling reveals the association of HbA1c and risk of hospitalization for heart failure for patients with type 2 diabetes mellitus. PLOS One 2023 Jan 20;18(1):e0275610. PMID: 36662791.
- Tan JK, Lim GH, Mohamed Salim NN, Chia SY, Thumboo J, Bee YM. Associations between mean HbA1c, HbA1c variability, and both mortality and macrovascular complications in patients with diabetes mellitus: A registry-based cohort study. Clinical Epidemiology 2023 Jan 25;15:137-149. PMID: 36721457.
- Rama Chandran S, Tan HC, Chen Q, Lee PC, Gardner DS, Chia YA, Lam AYR, Teh MM, Bee YM. Telemonitoring with a connected glucose meter improves glycemia among people with insulin-treated type 2 diabetes. Journal of Diabetes, Science and Technology 2023 Feb 24. Online ahead of print. PMID: 36825611.
- Sng GGR, Tung JYM, Lim DYZ, Bee YM. Potential and pitfalls of ChatGPT and natural-language artificial intelligence models for diabetes education. Diabetes Care. 2023 Mar 15. Online ahead of print. PMID: 36920843.
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