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VIRUS ISOLATION IN NEUROLOGICAL INFECTIONS

Synonym(s):

​Virus culture in neurological infections

Lab Section Category

Description

Indications

Specimen Required

​Throat swab, nasopharyngeal aspirate during the first 3 – 4 days of the illness

Stool

CSF

Swabs or scrapings of vesicles if present

Saliva (instead of throat swab or nasopharyngeal aspirate) and urine if mumps suspected

Brain biopsy for herpes encephalitis

Send samples (except stool, CSF, saliva & urine) in Virus Transport Medium.
(See also Virology Section, General Guidelines for Virus Isolation & Collection Methods for Virus Isolation by Sample Type)

Storage and Transport

​Refrigerate samples until transport to laboratory. Do not freeze.

Transport samples on ice pack to laboratory.

Method

​Tissue culture

Test Results

​Reported as Positive or Negative

Reference Interval / Value

Turnaround Time

​Positive report : 1 – 21 days

For enteroviruses – final report with enterovirus typing results : 2 – 6 weeks

Negative report : 21 days

Day(s) Test Set up

​Monday – Saturday

Remarks

​Viruses to be expected : Enterovirus, mumps, herpes simplex, varicella-zoster and influenza virus

Change History Notes

Others

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