SARS Total Ab, SARS IgM Ab, SARS IgG Ab
SARS-CoV IgM (anti-SARS IgM) SARS-CoV IgG (anti-SARS IgG) SARS-CoV Total Antibody (anti-SARS total)
6 – 8 mL plain blood in acute infection; 3 – 5 mL plain blood to diagnose past infection.(a) To diagnose acute SARS, send acute sample for IgM and total antibody, and a second sample two to three weeks later for IgM, IgG and total antibody. (b) To diagnose past infection, send one sample for IgG antibody.
Refrigerate samples if delay in transporting to laboratory is anticipated. Do not freeze.
Anti-SARS IgM: Immunofluorescence assay Anti-SARS IgG: Immunofluorescence assay Anti-SARS total: Enzyme Immunoassay
Acute infection: SARS IgM positive and confirmed by ≥ 4 fold rise of total Ab titres in paired sera or IgG seroconversion. Past infection: SARS IgG positive
Anti-SARS IgM or IgG : <1 – 4 days Anti-SARS total : 3 – 8 days
Anti-SARS IgM : Tuesday and FridayAnti-SARS IgG : Tuesday and FridayAnti-SARS total : Friday
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