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ANTI-NEUTROPHIL CYTOPLASMIC ANTIBODY (ANCA)

Synonym(s):

​Anti Neutrophil Cytoplasmic, ANCA, ANCA (IIF), C-ANCA, CANCA, P-ANCA, PANCA

Description

Indications

Specimen Required

​3 mL plain blood

Storage and Transport

Method

​Immunofluorescence

Test Results

​Screening dilution is 1:10.

Results reported as Negative; or Positive for P-ANCA, C-ANCA, Atypical ANCA, Atypical P-ANCA or Atypical C-ANCA.

C-ANCA positive cases will be diluted up to 1:40 for the first sample. The follow-up sample(s) will be diluted to endpoint in parallel with its previous sample for the monitoring of treatment.

Results are reported as Inconclusive for P-ANCA if anti-nuclear antibody is detected, as P-ANCA or atypical P-ANCA cannot be excluded.

For Inconclusive or Positive results, suggest anti-MPO and anti-PR3 testing.

Reference Interval / Value

Turnaround Time

​Range 2 – 4 days

Day(s) Test Set up

​Monday – Friday

Remarks

Change History Notes

Others

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